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rdf:type |
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|
lifeskim:mentions |
umls-concept:C0005791,
umls-concept:C0013081,
umls-concept:C0016441,
umls-concept:C0021390,
umls-concept:C0021745,
umls-concept:C0023516,
umls-concept:C0030705,
umls-concept:C0205210,
umls-concept:C0871261,
umls-concept:C1704632,
umls-concept:C1706817,
umls-concept:C2348042,
umls-concept:C2911692
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|
pubmed:issue |
6
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|
pubmed:dateCreated |
2006-7-21
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|
pubmed:abstractText |
Pilot studies have indicated a therapeutic role for an apheresis device (Adacolumn) that selectively adsorbs leukocytes in patients with inflammatory bowel diseases. It may also exert immunoregulatory effects contributing to its clinical efficacy. This study aimed to correlate the clinical response to leukocyte apheresis with the expression of key cytokines in mucosal tissue, in peripheral leukocytes, and in plasma.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
Sep
|
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pubmed:issn |
0179-1958
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
21
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
493-504
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:16538495-Adult,
pubmed-meshheading:16538495-Cell Membrane Permeability,
pubmed-meshheading:16538495-Colonoscopy,
pubmed-meshheading:16538495-Down-Regulation,
pubmed-meshheading:16538495-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16538495-Feasibility Studies,
pubmed-meshheading:16538495-Female,
pubmed-meshheading:16538495-Follow-Up Studies,
pubmed-meshheading:16538495-Humans,
pubmed-meshheading:16538495-Immunohistochemistry,
pubmed-meshheading:16538495-Inflammatory Bowel Diseases,
pubmed-meshheading:16538495-Interferon-gamma,
pubmed-meshheading:16538495-Intestinal Mucosa,
pubmed-meshheading:16538495-Leukapheresis,
pubmed-meshheading:16538495-Male,
pubmed-meshheading:16538495-Middle Aged,
pubmed-meshheading:16538495-Prospective Studies,
pubmed-meshheading:16538495-Time Factors,
pubmed-meshheading:16538495-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Down-regulation of interferon-gamma parallels clinical response to selective leukocyte apheresis in patients with inflammatory bowel disease: a 12-month follow-up study.
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pubmed:affiliation |
Department of Clinical Immunology and Transfusion Medicine, Karolinska University Hospital, Stockholm, 17176, Sweden. vladislaw.muratov@karolinska.se
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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