rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
2
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pubmed:dateCreated |
1991-10-9
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pubmed:databankReference |
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M72882,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M72883,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M73051,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M73052,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M73053,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M73054,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M73055,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/M73056,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S56131,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/S56173,
http://linkedlifedata.com/resource/pubmed/xref/GENBANK/X59843
|
pubmed:abstractText |
The VP6 gene of human group C rotavirus was cloned and sequenced. Hybridization to the human group C and the porcine group C/Cowden dsRNA genomes assigned this coding sequence to segment 5. The complete human VP6 sequence contained an open reading frame of 1185 nucleotides (395 amino acids; deduced Mr 44,669 Da). The protein sequence demonstrated low homology with the group A VP6 sequences (41.7 to 42.7%) and high homology (88.9%) with the porcine group C VP6 sequence. However, the protein sequence alignments revealed a region of 10 amino acids that were significantly different between the human and the porcine group C viruses.
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pubmed:language |
eng
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pubmed:journal |
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
pubmed:status |
MEDLINE
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pubmed:month |
Oct
|
pubmed:issn |
0042-6822
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
184
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
781-5
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1653500-Amino Acid Sequence,
pubmed-meshheading:1653500-Antigens, Viral,
pubmed-meshheading:1653500-Base Sequence,
pubmed-meshheading:1653500-Blotting, Northern,
pubmed-meshheading:1653500-Capsid,
pubmed-meshheading:1653500-Capsid Proteins,
pubmed-meshheading:1653500-Cloning, Molecular,
pubmed-meshheading:1653500-DNA,
pubmed-meshheading:1653500-Genes, Viral,
pubmed-meshheading:1653500-Humans,
pubmed-meshheading:1653500-Molecular Sequence Data,
pubmed-meshheading:1653500-Oligonucleotides,
pubmed-meshheading:1653500-Polymerase Chain Reaction,
pubmed-meshheading:1653500-RNA, Viral,
pubmed-meshheading:1653500-Rotavirus,
pubmed-meshheading:1653500-Viral Structural Proteins
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pubmed:year |
1991
|
pubmed:articleTitle |
Molecular cloning, sequence analysis and coding assignment of the major inner capsid protein gene of human group C rotavirus.
|
pubmed:affiliation |
Department of Microbiology, University Medical School, Southampton General Hospital, United Kingdom.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|