Linked Life Data

16534614

Source:http://linkedlifedata.com/resource/pubmed/id/16534614

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
5
pubmed:dateCreated
2006-8-9
pubmed:abstractText
SHetA2 {[(4-nitrophenyl)amino][2,2,4,4-tetramethylthiochroman-6-yl)amino]methane-thione], NSC 726189} is a sulfur-containing heteroarotinoid, which selectively inhibits cancer cell growth and induces apoptosis without activation of nuclear retinoic acid receptors (RARs). The objective was to develop and validate a HPLC/UV method for the determination of SHetA2, and study the pharmacokinetics of SHetA2 in the mouse.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
0344-5704
pubmed:author
pubmed:issnType
Print
pubmed:volume
58
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
561-9
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed-meshheading:16534614-Administration, Oral, pubmed-meshheading:16534614-Animals, pubmed-meshheading:16534614-Antineoplastic Agents, pubmed-meshheading:16534614-Area Under Curve, pubmed-meshheading:16534614-Biological Availability, pubmed-meshheading:16534614-Chromans, pubmed-meshheading:16534614-Chromatography, High Pressure Liquid, pubmed-meshheading:16534614-Dogs, pubmed-meshheading:16534614-Drug Screening Assays, Antitumor, pubmed-meshheading:16534614-Drug Stability, pubmed-meshheading:16534614-Half-Life, pubmed-meshheading:16534614-Humans, pubmed-meshheading:16534614-Injections, Intravenous, pubmed-meshheading:16534614-Mass Spectrometry, pubmed-meshheading:16534614-Mice, pubmed-meshheading:16534614-Mice, Inbred Strains, pubmed-meshheading:16534614-Molecular Structure, pubmed-meshheading:16534614-Rats, pubmed-meshheading:16534614-Retinoids, pubmed-meshheading:16534614-Temperature, pubmed-meshheading:16534614-Thiones
pubmed:year
2006
pubmed:articleTitle
High performance liquid chromatographic analysis and preclinical pharmacokinetics of the heteroarotinoid antitumor agent, SHetA2.
pubmed:affiliation
College of Pharmacy, The Ohio State University, Columbus, OH 43210, USA.
pubmed:publicationType
Journal Article, Comparative Study