Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3
pubmed:dateCreated
2006-3-14
pubmed:abstractText
This study examined baseline correlates of substance use in the NIMH Clinical Antipsychotic Trials of Intervention Effectiveness project. Approximately 60% of the sample was found to use substances, including 37% with current evidence of substance use disorders. Users (with and without substance use disorders), compared with nonusers, were significantly more likely to be male, be African-American, have lower educational attainment, have a recent period of homelessness, report more childhood conduct problems, have a history of major depression, have lower negative symptom and higher positive symptom scores on the Positive and Negative Syndrome Scale, and have a recent illness exacerbation. Individuals with comorbid substance use disorders were significantly more likely to be male, report more childhood conduct problems, have higher positive symptom scores on the Positive and Negative Syndrome Scale, and have a recent illness exacerbation. These analyses suggest that substance use disorders in schizophrenia are especially common among men with a history of childhood conduct disorder problems and that childhood conduct disorder problems are potent risk factors for substance use disorders in schizophrenia.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
AIM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0022-3018
pubmed:author
pubmed:issnType
Print
pubmed:volume
194
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
164-72
pubmed:dateRevised
2007-11-15
pubmed:meshHeading
pubmed-meshheading:16534433-Antipsychotic Agents, pubmed-meshheading:16534433-Comorbidity, pubmed-meshheading:16534433-Conduct Disorder, pubmed-meshheading:16534433-Cross-Sectional Studies, pubmed-meshheading:16534433-Diagnosis, Dual (Psychiatry), pubmed-meshheading:16534433-Double-Blind Method, pubmed-meshheading:16534433-Female, pubmed-meshheading:16534433-Humans, pubmed-meshheading:16534433-Male, pubmed-meshheading:16534433-Multicenter Studies as Topic, pubmed-meshheading:16534433-Piperazines, pubmed-meshheading:16534433-Prevalence, pubmed-meshheading:16534433-Randomized Controlled Trials as Topic, pubmed-meshheading:16534433-Risk Factors, pubmed-meshheading:16534433-Schizophrenia, pubmed-meshheading:16534433-Schizophrenic Psychology, pubmed-meshheading:16534433-Sex Factors, pubmed-meshheading:16534433-Substance-Related Disorders, pubmed-meshheading:16534433-Thiazoles, pubmed-meshheading:16534433-Treatment Outcome, pubmed-meshheading:16534433-United States
pubmed:year
2006
pubmed:articleTitle
Substance use in persons with schizophrenia: baseline prevalence and correlates from the NIMH CATIE study.
pubmed:affiliation
Department of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC 27710, USA.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't, Research Support, N.I.H., Extramural