Linked Life Data

16533924

Source:http://linkedlifedata.com/resource/pubmed/id/16533924

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-3-14
pubmed:abstractText
Mammalian cells are continuously subject to insult from reactive species. Most of the pathogenic mechanisms that have been considered to date reflect overproduction of reactive oxygen species (ROS) or a peculiar failure in intracellular defenses against ROS. We have attempted to consider briefly the most important mechanisms of ROS production, defense, and reactive species-induced cell damage and approaches to therapy, focusing on the example of diabetes mellitus. An improved understanding of these mechanisms should facilitate development of antioxidant intervention strategies leading to reduction in diseases associated with oxidative stress.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0077-8923
pubmed:author
pubmed:issnType
Print
pubmed:volume
1066
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
136-51
pubmed:dateRevised
2007-11-14
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
Oxidative reactive species in cell injury: Mechanisms in diabetes mellitus and therapeutic approaches.
pubmed:affiliation
Department of Medicine, MC-1027, The University of Chicago, 5841 S. Maryland Ave., Chicago, IL 60637, USA.
pubmed:publicationType
Journal Article, Review, Research Support, N.I.H., Extramural