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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
|
pubmed:dateCreated |
1991-10-7
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pubmed:abstractText |
The prevalence of antibody to hepatitis C virus (anti-HCV) was investigated in patients with hepatocellular carcinoma (HCC), and correlated with the clinical features. Anti-HCV was detected in 129 histology or aspiration cytology proven HCC patients and 54 healthy controls. Anti-HCV was examined by the HCV EIA (Abbott Laboratories). All healthy controls were anti-HCV-negative. Nineteen of 81 (23.5%) hepatitis B surface antigen (HBsAg)-positive HCC patients were positive for anti-HCV. Anti-HCV was found among 60.4% (29/48) of HCC patients without detectable HB-sAg. Forty-eight of 129 (37.2%) HCC patients were positive for anti-HCV. There was a significant difference in the prevalence of anti-HCV between patients with HBsAg (23.5%) and those without HBsAg (60.4%, P = 0.0001). However, irrespective of the status of HBsAg, there was no statistical difference in sex, age, routine liver function tests, alpha-fetoprotein concentration, or associated cirrhosis between patients with anti-HCV and those without. The results imply that hepatitis C virus may play a role in the pathogenesis of HCC.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0146-6615
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
74-7
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pubmed:dateRevised |
2004-11-17
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pubmed:meshHeading |
pubmed-meshheading:1653308-Adult,
pubmed-meshheading:1653308-Age Factors,
pubmed-meshheading:1653308-Aged,
pubmed-meshheading:1653308-Carcinoma, Hepatocellular,
pubmed-meshheading:1653308-Female,
pubmed-meshheading:1653308-Hepacivirus,
pubmed-meshheading:1653308-Hepatitis, Chronic,
pubmed-meshheading:1653308-Hepatitis B Surface Antigens,
pubmed-meshheading:1653308-Hepatitis C,
pubmed-meshheading:1653308-Humans,
pubmed-meshheading:1653308-Liver Neoplasms,
pubmed-meshheading:1653308-Male,
pubmed-meshheading:1653308-Middle Aged,
pubmed-meshheading:1653308-Sex Factors,
pubmed-meshheading:1653308-Taiwan
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pubmed:year |
1991
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pubmed:articleTitle |
Hepatitis C virus antibody in hepatocellular carcinoma in Taiwan.
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pubmed:affiliation |
Department of Clinical Laboratory Medicine, Kaohsiung Medical College, Republic of China.
|
pubmed:publicationType |
Journal Article,
Case Reports
|