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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-3-13
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pubmed:abstractText |
Fatty acid ethyl esters are ethanol metabolites inducing sustained, toxic elevations of the acinar cytosolic free calcium ion concentration ([Ca(2+)](C)) implicated in pancreatitis. We sought to define the mechanisms of this elevation.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Adenosine Triphosphate,
http://linkedlifedata.com/resource/pubmed/chemical/Caffeine,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium Channels,
http://linkedlifedata.com/resource/pubmed/chemical/Calcium-Transporting ATPases,
http://linkedlifedata.com/resource/pubmed/chemical/Ethanol,
http://linkedlifedata.com/resource/pubmed/chemical/Fatty Acids,
http://linkedlifedata.com/resource/pubmed/chemical/Inositol 1,4,5-Trisphosphate...,
http://linkedlifedata.com/resource/pubmed/chemical/Receptors, Cytoplasmic and Nuclear
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0016-5085
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
130
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
781-93
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16530519-Adenosine Triphosphate,
pubmed-meshheading:16530519-Animals,
pubmed-meshheading:16530519-Caffeine,
pubmed-meshheading:16530519-Calcium,
pubmed-meshheading:16530519-Calcium Channels,
pubmed-meshheading:16530519-Calcium Signaling,
pubmed-meshheading:16530519-Calcium-Transporting ATPases,
pubmed-meshheading:16530519-Endoplasmic Reticulum,
pubmed-meshheading:16530519-Ethanol,
pubmed-meshheading:16530519-Fatty Acids,
pubmed-meshheading:16530519-Inositol 1,4,5-Trisphosphate Receptors,
pubmed-meshheading:16530519-Mice,
pubmed-meshheading:16530519-Mitochondria,
pubmed-meshheading:16530519-Pancreas,
pubmed-meshheading:16530519-Pancreatitis, Alcoholic,
pubmed-meshheading:16530519-Receptors, Cytoplasmic and Nuclear
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pubmed:year |
2006
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pubmed:articleTitle |
Fatty acid ethyl esters cause pancreatic calcium toxicity via inositol trisphosphate receptors and loss of ATP synthesis.
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pubmed:affiliation |
Medical Research Council Secretory Control Research Group, Physiological Laboratory, University of Liverpool, Liverpool, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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