Linked Life Data

16524764

Source:http://linkedlifedata.com/resource/pubmed/id/16524764

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
3-4
pubmed:dateCreated
2006-10-10
pubmed:abstractText
The reaction of [Cr(urea)(6)]Cl(3).3H(2)O with H(2)salen (H(2)salen=N,N(')-ethylenebis(salicylaldimine) in water-methanol mixture (40:60v/v) under reflux yielded the complex bis[N-(2-aminoethyl)salicylaldiminato]chromium(III) chloride monohydrate, [Cr(aesaldmn)(2)]Cl.H(2)O. The complex was characterized by elemental analysis, molar conductance, magnetic susceptibility, spectroscopic (UV-vis and IR) data and X-ray diffraction studies. The new ligand, N-(2-aminoethyl)salicylaldimine, Haesaldmn, possibly resulted from the hydrolytic cleavage of one end of the H(2)salen ligand during reflux. Binding of this chromium(III) complex to CT DNA has been studied using UV-vis spectroscopy with an apparent binding constant of 2.68 x 10(3)M(-1). It shows that the binding mode is electrostatic while the emission of ethidium bromide to CT DNA in the absence and in the presence of the complex show that it binds DNA with partial intercalation.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Nov
pubmed:issn
1386-1425
pubmed:author
pubmed:issnType
Print
pubmed:volume
65
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
523-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
New route to the synthesis of bis[N-(2-aminoethyl) salicylaldiminato] chromium(III) chloride monohydrate Spectroscopic characterization, crystal structure and interaction with DNA.
pubmed:affiliation
Department of Chemistry, University of Kalyani, Kalyani 741235, India.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't