Linked Life Data

1652373

Source:http://linkedlifedata.com/resource/pubmed/id/1652373

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
1991-9-27
pubmed:abstractText
A noninvasive method for monitoring communications on DNA was developed from the specificity of resolvase for the arrangement of its recombinational sites. Constraints in DNA structure, caused by interactions between distant sites, can be detected by resolvase as they arise. The method was used to follow the formation and decay of synaptic intermediates during site-specific recombination by resolvase. Synaptic complexes were formed very rapidly, at a rate limited by the initial association of the protein with DNA rather than the physical motion of DNA segments. The recombinational sites seem to encounter each other by an ordered motion, perhaps dictated by DNA supercoiling instead of random collisions, so that the first encounter produces the active complex.
pubmed:grant
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Aug
pubmed:issn
0092-8674
pubmed:author
pubmed:issnType
Print
pubmed:day
23
pubmed:volume
66
pubmed:geneSymbol
res
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
781-91
pubmed:dateRevised
2009-9-29
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Dynamics of long-range interactions on DNA: the speed of synapsis during site-specific recombination by resolvase.
pubmed:affiliation
Department of Biochemistry, University of Bristol, England.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't