rdf:type |
|
lifeskim:mentions |
umls-concept:C0002085,
umls-concept:C0009491,
umls-concept:C0032659,
umls-concept:C0033105,
umls-concept:C0066357,
umls-concept:C0178638,
umls-concept:C0238606,
umls-concept:C0239307,
umls-concept:C0240339,
umls-concept:C0449438,
umls-concept:C1579762
|
pubmed:issue |
3
|
pubmed:dateCreated |
2006-3-8
|
pubmed:abstractText |
Methylenetetrahydrofolate reductase (MTHFR) 677C-->T polymorphism is heterogeneously distributed worldwide, with the highest and lowest frequencies of the T allele in Mexico and Africa, respectively, and a south-to-north gradient in Europe. Distribution of MTHFR 1298A-->C is less well known. It has been hypothesized that 677T frequency could result in part from gene-nutrient interactions.
|
pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
AIM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
0002-9165
|
pubmed:author |
pubmed-author:AmouzouEmileE,
pubmed-author:AnelloGuidoG,
pubmed-author:ArrietaHeidy RHR,
pubmed-author:BoscoPaoloP,
pubmed-author:BronowickiJean-PierreJP,
pubmed-author:ChabiNicodème WNW,
pubmed-author:DebardRenéeR,
pubmed-author:Guéant-RodriguezRosa-MariaRM,
pubmed-author:GuéantJean-LouisJL,
pubmed-author:GuillandJean-ClaudeJC,
pubmed-author:HerbethBernardB,
pubmed-author:HongLu XiaoLX,
pubmed-author:MutchinickOsvaldo MOM,
pubmed-author:NamourFarèsF,
pubmed-author:RomanoAntoninoA,
pubmed-author:RomanoCorradoC,
pubmed-author:SánchezBeatríz EBE,
pubmed-author:SanniAmbaliouA,
pubmed-author:ThirionSylvieS
|
pubmed:issnType |
Print
|
pubmed:volume |
83
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
701-7
|
pubmed:dateRevised |
2006-12-14
|
pubmed:meshHeading |
pubmed-meshheading:16522920-Adolescent,
pubmed-meshheading:16522920-Adult,
pubmed-meshheading:16522920-Africa, Western,
pubmed-meshheading:16522920-Alleles,
pubmed-meshheading:16522920-Europe,
pubmed-meshheading:16522920-Female,
pubmed-meshheading:16522920-Folic Acid,
pubmed-meshheading:16522920-Gene Frequency,
pubmed-meshheading:16522920-Genotype,
pubmed-meshheading:16522920-Homocysteine,
pubmed-meshheading:16522920-Humans,
pubmed-meshheading:16522920-Male,
pubmed-meshheading:16522920-Methylenetetrahydrofolate Reductase (NADPH2),
pubmed-meshheading:16522920-Mexico,
pubmed-meshheading:16522920-Middle Aged,
pubmed-meshheading:16522920-Polymorphism, Genetic,
pubmed-meshheading:16522920-Regression Analysis,
pubmed-meshheading:16522920-Vitamin B 12
|
pubmed:year |
2006
|
pubmed:articleTitle |
Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations.
|
pubmed:affiliation |
INSERM U-724, Cellular and Molecular Pathology in Nutrition, Faculté de Médecine, University Henry Poincaré of Nancy, Vandoeuvre lès Nancy, France.
|
pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't
|