|
rdf:type |
|
|
lifeskim:mentions |
|
|
pubmed:issue |
10
|
|
pubmed:dateCreated |
2006-3-8
|
|
pubmed:abstractText |
The association between coffee intake and risk of myocardial infarction (MI) remains controversial. Coffee is a major source of caffeine, which is metabolized by the polymorphic cytochrome P450 1A2 (CYP1A2) enzyme. Individuals who are homozygous for the CYP1A2*1A allele are "rapid" caffeine metabolizers, whereas carriers of the variant CYP1A2*1F are "slow" caffeine metabolizers.
|
|
pubmed:grant |
|
|
pubmed:commentsCorrections |
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
AIM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:month |
Mar
|
|
pubmed:issn |
1538-3598
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:day |
8
|
|
pubmed:volume |
295
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
1135-41
|
|
pubmed:dateRevised |
2007-11-15
|
|
pubmed:meshHeading |
pubmed-meshheading:16522833-Aged,
pubmed-meshheading:16522833-Amino Acid Substitution,
pubmed-meshheading:16522833-Catchment Area (Health),
pubmed-meshheading:16522833-Coffee,
pubmed-meshheading:16522833-Costa Rica,
pubmed-meshheading:16522833-Cytochrome P-450 CYP1A2,
pubmed-meshheading:16522833-Female,
pubmed-meshheading:16522833-Genotype,
pubmed-meshheading:16522833-Humans,
pubmed-meshheading:16522833-Logistic Models,
pubmed-meshheading:16522833-Male,
pubmed-meshheading:16522833-Middle Aged,
pubmed-meshheading:16522833-Myocardial Infarction,
pubmed-meshheading:16522833-Polymerase Chain Reaction,
pubmed-meshheading:16522833-Polymorphism, Restriction Fragment Length,
pubmed-meshheading:16522833-Risk Factors
|
|
pubmed:year |
2006
|
|
pubmed:articleTitle |
Coffee, CYP1A2 genotype, and risk of myocardial infarction.
|
|
pubmed:affiliation |
Department of Nutritional Sciences, University of Toronto, Toronto, Ontario, Canada.
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
|
