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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-3-8
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pubmed:abstractText |
Activation of the renin-angiotensin (RAS) cascade and sympathetic nervous systems adversely affect heart failure progression. ACE deletion allele (ACE D) of insertion/deletion polymorphism in the gene coding for angiotensin-1 converting enzyme is associated with increased renin-angiotensin activation. The aim of the study was to test pharmacogenetic associations of I/D ACE genotype with beta blockers therapy in patients with chronic heart failure.
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pubmed:language |
cze
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:issn |
0008-7335
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
145
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
148-52; discussion 152-3
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pubmed:dateRevised |
2007-11-15
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pubmed:meshHeading |
pubmed-meshheading:16521406-Adrenergic beta-Antagonists,
pubmed-meshheading:16521406-Adult,
pubmed-meshheading:16521406-Aged,
pubmed-meshheading:16521406-Aged, 80 and over,
pubmed-meshheading:16521406-Female,
pubmed-meshheading:16521406-Gene Frequency,
pubmed-meshheading:16521406-Genotype,
pubmed-meshheading:16521406-Heart Failure,
pubmed-meshheading:16521406-Humans,
pubmed-meshheading:16521406-Male,
pubmed-meshheading:16521406-Middle Aged,
pubmed-meshheading:16521406-Peptidyl-Dipeptidase A,
pubmed-meshheading:16521406-Polymorphism, Genetic
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|
pubmed:year |
2006
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pubmed:articleTitle |
[Pharmacogenetics of chronic heart failure--beta blockers].
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pubmed:affiliation |
Ustav patologické fyziologie LF MU, Brno. avasku@med.muni.cz
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pubmed:publicationType |
Journal Article,
English Abstract
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