Source:http://linkedlifedata.com/resource/pubmed/id/16519474
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
6
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pubmed:dateCreated |
2006-3-7
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pubmed:abstractText |
SU-8 has gained widespread acceptance as a negative photoresist. It is also finding increasing use as a structural material in microanalytical devices. Consequently, methods to tailor the surface properties of SU-8 as well as to micropattern coatings on the surface of SU-8 are needed. The SU-8 photoresist consists of EPON SU-8 resin mixed with the photoacid generator triarylsulfonium hexafluoroantimonate. This photoacid generator can also serve as a photoinitiator generating free radicals when illuminated with UV light. Under the appropriate conditions, sufficient triarylsulfonium hexafluoroantimonate remains within cured SU-8 to act as a source of free radicals and initiate UV-mediated grafting of polymers onto the surface of the SU-8. UV-mediated grafting was used to coat SU-8 surfaces with poly(acrylic acid) and other water-soluble monomers. The SU-8 surface was chemically micropatterned by placing a mask between the UV light and SU-8. The X-Y spatial resolution of micropatterned poly(acrylic acid) on the SU-8 surface was 2 mum. Three applications of these chemically modified SU-8 surfaces were demonstrated. In the first, poly(ethylene glycol) was used to protect the SU-8 from interactions with proteins, yielding a surface resistant to biofouling. In the second demonstration, the SU-8 surface was micropatterned with a cell-resistant layer to guide cellular attachment and growth. In the final application, SU-8 micropallets were encoded with polymer lines. The bar codes were read by either absorbance or fluorescence measurements. Thus, UV-mediated graft polymerization is an efficient and effective method to micropattern coatings onto the surface of SU-8.
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pubmed:grant | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0743-7463
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
14
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pubmed:volume |
22
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
2719-25
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pubmed:dateRevised |
2007-12-3
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pubmed:meshHeading |
pubmed-meshheading:16519474-Animals,
pubmed-meshheading:16519474-Cell Division,
pubmed-meshheading:16519474-Cells, Cultured,
pubmed-meshheading:16519474-Microscopy, Atomic Force,
pubmed-meshheading:16519474-Photochemistry,
pubmed-meshheading:16519474-Rats,
pubmed-meshheading:16519474-Semiconductors,
pubmed-meshheading:16519474-Spectroscopy, Fourier Transform Infrared,
pubmed-meshheading:16519474-Surface Properties,
pubmed-meshheading:16519474-Ultraviolet Rays
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pubmed:year |
2006
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pubmed:articleTitle |
Simple photografting method to chemically modify and micropattern the surface of SU-8 photoresist.
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pubmed:affiliation |
Integrated Nanosystems Research Facility, Department of Electrical Engineering and Computer Science, University of California, Irvine, California 92697, USA.
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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