Source:http://linkedlifedata.com/resource/pubmed/id/16516567
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-6-12
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pubmed:abstractText |
To establish a method for separating the optical isomers of lactic acid, we modified the derivatization steps in our procedure for urinary mass-screening for inborn errors of metabolism. For chiral recognition, we chose O-trifluoroacetyl-(-)-menthylation derivatization instead of our previous method, trimethylsilyl derivatization, and the samples were then analyzed under GC/MS by capillary gas chromatography on a DB-5MS column. This method can be used to follow-up the condition of a patient with short bowel syndrome and to prevent onset and/or seizure. d-Lactic acid was also isolated from the urine of healthy controls as one of the main peaks in the chromatogram.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
1570-0232
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:day |
21
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pubmed:volume |
838
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
37-42
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16516567-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:16516567-Humans,
pubmed-meshheading:16516567-Lactic Acid,
pubmed-meshheading:16516567-Male,
pubmed-meshheading:16516567-Molecular Structure,
pubmed-meshheading:16516567-Reproducibility of Results,
pubmed-meshheading:16516567-Sensitivity and Specificity,
pubmed-meshheading:16516567-Short Bowel Syndrome,
pubmed-meshheading:16516567-Stereoisomerism
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pubmed:year |
2006
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pubmed:articleTitle |
Application of optical isomer analysis by diastereomer derivatization GC/MS to determine the condition of patients with short bowel syndrome.
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pubmed:affiliation |
Division of Human Genetics, Medical Research Institute, Kanazawa Medical University, 1-1 Daigaku, Uchinada, Ishikawa 9200293, Japan. yosh@kanazawa-med.ac.jp
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pubmed:publicationType |
Journal Article
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