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pubmed-article:16513443pubmed:abstractTextOur objective was to learn whether genetic polymorphisms of metabolic enzymes or transport proteins provide a mechanistic understanding of the in vivo disposition of atrasentan, a selective endothelin A receptor antagonist.lld:pubmed
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pubmed-article:16513443pubmed:articleTitleOrganic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.lld:pubmed
pubmed-article:16513443pubmed:affiliationDepartment of Pharmacogenetics, Abbott Laboratories, Abbott Park, IL 60064, USA. david.katz@abbott.comlld:pubmed
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