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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-3-3
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pubmed:abstractText |
Our objective was to learn whether genetic polymorphisms of metabolic enzymes or transport proteins provide a mechanistic understanding of the in vivo disposition of atrasentan, a selective endothelin A receptor antagonist.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0009-9236
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pubmed:author |
pubmed-author:AllenAndrewA,
pubmed-author:CarrRobertR,
pubmed-author:DoanThaoT,
pubmed-author:EdekiTimiT,
pubmed-author:GrimmDavid RDR,
pubmed-author:HanLixinL,
pubmed-author:Holley-ShanksRhondaR,
pubmed-author:KatzDavid ADA,
pubmed-author:KimRichard BRB,
pubmed-author:LeakeBrendaB,
pubmed-author:MuellerTobyT,
pubmed-author:SahelijoLeonardoL,
pubmed-author:SpearBrian BBB,
pubmed-author:WangPerry GPG,
pubmed-author:WangQiangQ,
pubmed-author:XiongHaoH
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pubmed:issnType |
Print
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pubmed:volume |
79
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
186-96
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16513443-Adult,
pubmed-meshheading:16513443-Alleles,
pubmed-meshheading:16513443-Carrier Proteins,
pubmed-meshheading:16513443-Female,
pubmed-meshheading:16513443-Genotype,
pubmed-meshheading:16513443-HeLa Cells,
pubmed-meshheading:16513443-Humans,
pubmed-meshheading:16513443-Male,
pubmed-meshheading:16513443-Middle Aged,
pubmed-meshheading:16513443-Organic Anion Transporters,
pubmed-meshheading:16513443-Phenotype,
pubmed-meshheading:16513443-Pyrrolidines,
pubmed-meshheading:16513443-Transfection
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pubmed:year |
2006
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pubmed:articleTitle |
Organic anion transporting polypeptide 1B1 activity classified by SLCO1B1 genotype influences atrasentan pharmacokinetics.
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pubmed:affiliation |
Department of Pharmacogenetics, Abbott Laboratories, Abbott Park, IL 60064, USA. david.katz@abbott.com
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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