Linked Life Data

16512089

Source:http://linkedlifedata.com/resource/pubmed/id/16512089

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
6
pubmed:dateCreated
2006-3-3
pubmed:abstractText
Eosinophilic esophagitis (EE), first recognized as a unique entity somewhat more than 10 years ago, is a chronic, TH2-type inflammatory disorder of the esophagus. The diagnostic criterion is a peak infiltration of the esophageal epithelium with >24 eosinophils/HPF. The inflammatory pattern consists of eosinophils, T-cells and mast cells, together with increased expression of IL-5 and TNF-alpha. Though originally believed extremely rare, EE is increasingly recognized and its prevalence may soon equal chronic inflammatory bowel diseases. The main symptom of EE is dysphagia for solid foods with imminent risk of food impaction. Endoscopic abnormalities are varied but discreet, with reddish furrows being the most frequent and white exudates being the most prominent sign. The main long-term risk of EE is the induction of fibrosis with subsequent esophageal stricture. Therapeutic recommendations include systemic or topical corticosteroids, leukotriene antagonists, hypo-allergic diets and dilation.
pubmed:language
ger
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Jan
pubmed:issn
1661-8157
pubmed:author
pubmed:issnType
Print
pubmed:day
25
pubmed:volume
95
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
191-5
pubmed:dateRevised
2008-6-10
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
[Eosinophilic esophagitis: a novel entity?].
pubmed:affiliation
Abteilung für Gastroenterologie, Medizinische Klinik, Kantonsspital, Olten. alex.straumann@hin.ch
pubmed:publicationType
Journal Article, English Abstract