Linked Life Data

16511799

Source:http://linkedlifedata.com/resource/pubmed/id/16511799

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-3-2
pubmed:abstractText
An adult, male, green iguana (Iguana iguana) of unknown age was presented with a history of an enlarging, dark, skin mass in the right axillary region. The mass was excised because neoplasia was suspected. Impression smears of the cut surface of the mass were prepared for cytologic examination, and the mass was fixed for histologic examination. The impression smears contained numerous, discrete, pigmented, neoplastic cells consistent with melanin-producing neoplastic chromatophores. Histologic findings were consistent with a cutaneous melanophoroma. By transmission electron microscopy, the intracytoplasmic pigment granules corresponded to numerous melanosomes and lower numbers of premelanosomes. Tissue sections of the tumor were immunoreactive for Melan A antigen and were negative for S-100 antigen. The cytologic, histologic, electron microscopic, and immunohistochemical findings of the neoplasm were consistent with those of melanophoroma, an uncommon neoplasm of reptiles. The present report augments the limited body of knowledge on cytomorphologic and immunohistochemical characteristics of pigmented neoplasms in reptiles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0275-6382
pubmed:author
pubmed:issnType
Print
pubmed:volume
35
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
101-5
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Cutaneous melanophoroma in a green iguana (Iguana iguana).
pubmed:affiliation
Eli Lilly and Company, Lilly Research Laboratories, Greenfield, IN, USA. irizarryar@lilly.com
pubmed:publicationType
Journal Article, Case Reports