Linked Life Data

16511223

Source:http://linkedlifedata.com/resource/pubmed/id/16511223

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pubmed-article:16511223pubmed:dateCreated2006-3-2lld:pubmed
pubmed-article:16511223pubmed:abstractTextFatty acid-CoA racemase plays an important role in the beta-oxidation of branched-chain fatty acids and fatty-acid derivatives as it catalyzes the conversion of several (2R)-branched-chain fatty acid-CoAs to their (2S)-stereoisomers. Fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv has been purified to homogeneity and crystallized by the hanging-drop vapour-diffusion method with polyethylene glycol 4000 as precipitant. The crystals belong to the trigonal space group P3(1) or P3(2), with unit-cell parameters a = b = 109.56, c = 147.97 A. The asymmetric unit contains six monomers, corresponding to a VM value of 2.15 A3 Da(-1). A complete native data set has been collected at 2.7 A resolution using a synchrotron-radiation source.lld:pubmed
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pubmed-article:16511223pubmed:articleTitleCrystallization and preliminary X-ray crystallographic studies of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv.lld:pubmed
pubmed-article:16511223pubmed:affiliationBiomedical Research Center, Division of Life Sicence, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Sungbuk-gu, Seoul 136-791, South Korea.lld:pubmed
pubmed-article:16511223pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:16511223pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
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