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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
Pt 11
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pubmed:dateCreated |
2006-3-2
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pubmed:abstractText |
Fatty acid-CoA racemase plays an important role in the beta-oxidation of branched-chain fatty acids and fatty-acid derivatives as it catalyzes the conversion of several (2R)-branched-chain fatty acid-CoAs to their (2S)-stereoisomers. Fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv has been purified to homogeneity and crystallized by the hanging-drop vapour-diffusion method with polyethylene glycol 4000 as precipitant. The crystals belong to the trigonal space group P3(1) or P3(2), with unit-cell parameters a = b = 109.56, c = 147.97 A. The asymmetric unit contains six monomers, corresponding to a VM value of 2.15 A3 Da(-1). A complete native data set has been collected at 2.7 A resolution using a synchrotron-radiation source.
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pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-10191284,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-11893780,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-12554951,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-12633678,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-15464416,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-15632186,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-5700707,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-7545216,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-8125050,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-942051,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-9469587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16511223-9757107
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Nov
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pubmed:issn |
1744-3091
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
1
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pubmed:volume |
61
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1017-9
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pubmed:dateRevised |
2009-11-18
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pubmed:meshHeading |
pubmed-meshheading:16511223-Acyl-CoA Oxidase,
pubmed-meshheading:16511223-Crystallization,
pubmed-meshheading:16511223-Crystallography, X-Ray,
pubmed-meshheading:16511223-Fatty Acids,
pubmed-meshheading:16511223-Mycobacterium tuberculosis,
pubmed-meshheading:16511223-Oxygen,
pubmed-meshheading:16511223-Polyethylene Glycols,
pubmed-meshheading:16511223-Protein Conformation,
pubmed-meshheading:16511223-Racemases and Epimerases,
pubmed-meshheading:16511223-Recombinant Proteins,
pubmed-meshheading:16511223-Stereoisomerism,
pubmed-meshheading:16511223-Synchrotrons,
pubmed-meshheading:16511223-X-Ray Diffraction
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pubmed:year |
2005
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pubmed:articleTitle |
Crystallization and preliminary X-ray crystallographic studies of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv.
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pubmed:affiliation |
Biomedical Research Center, Division of Life Sicence, Korea Institute of Science and Technology, 39-1 Hawolgok-dong, Sungbuk-gu, Seoul 136-791, South Korea.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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