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16510744
Source:
http://linkedlifedata.com/resource/pubmed/id/16510744
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Statements in which the resource exists as a subject.
Predicate
Object
rdf:type
pubmed:Citation
lifeskim:mentions
umls-concept:C0008976
,
umls-concept:C0026769
,
umls-concept:C0034656
,
umls-concept:C0035020
,
umls-concept:C1172734
pubmed:issue
9
pubmed:dateCreated
2006-3-2
pubmed:databankReference
http://linkedlifedata.com/resource/pubmed/xref/ClinicalTrials.gov/NCT00027300
pubmed:abstractText
Natalizumab is the first alpha4 integrin antagonist in a new class of selective adhesion-molecule inhibitors. We report the results of a two-year phase 3 trial of natalizumab in patients with relapsing multiple sclerosis.
pubmed:grant
http://linkedlifedata.com/resource/pubmed/grant/748
pubmed:commentsCorrections
http://linkedlifedata.com/resource/pubmed/commentcorrection/16510744-16510751
,
http://linkedlifedata.com/resource/pubmed/commentcorrection/16510744-16738278
pubmed:language
eng
pubmed:journal
http://linkedlifedata.com/resource/pubmed/journal/0255562
pubmed:citationSubset
AIM
pubmed:chemical
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal
,
http://linkedlifedata.com/resource/pubmed/chemical/Antibodies, Monoclonal, Humanized
,
http://linkedlifedata.com/resource/pubmed/chemical/Cell Adhesion Molecules
,
http://linkedlifedata.com/resource/pubmed/chemical/Integrin alpha4
,
http://linkedlifedata.com/resource/pubmed/chemical/natalizumab
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
1533-4406
pubmed:author
pubmed-author:AFFIRM Investigators
,
pubmed-author:GiovannoniGavinG
,
pubmed-author:HavrdovaEvaE
,
pubmed-author:HutchinsonMichaelM
,
pubmed-author:KapposLudwigL
,
pubmed-author:LublinFred DFD
,
pubmed-author:LynnFrancesF
,
pubmed-author:MillerDavid HDH
,
pubmed-author:O'ConnorPaul WPW
,
pubmed-author:PanzaraMichael AMA
,
pubmed-author:PhillipsJ TheodoreJT
,
pubmed-author:PolmanChris HCH
,
pubmed-author:SandrockAlfred WAW
,
pubmed-author:ToalMartinM
,
pubmed-author:WajgtAndrzejA
pubmed:copyrightInfo
Copyright 2006 Massachusetts Medical Society.
pubmed:issnType
Electronic
pubmed:day
2
pubmed:volume
354
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
899-910
pubmed:dateRevised
2011-11-17
pubmed:meshHeading
pubmed-meshheading:16510744-Adolescent
,
pubmed-meshheading:16510744-Adult
,
pubmed-meshheading:16510744-Antibodies, Monoclonal
,
pubmed-meshheading:16510744-Antibodies, Monoclonal, Humanized
,
pubmed-meshheading:16510744-Brain
,
pubmed-meshheading:16510744-Cell Adhesion Molecules
,
pubmed-meshheading:16510744-Disease Progression
,
pubmed-meshheading:16510744-Drug Hypersensitivity
,
pubmed-meshheading:16510744-Fatigue
,
pubmed-meshheading:16510744-Female
,
pubmed-meshheading:16510744-Humans
,
pubmed-meshheading:16510744-Infusions, Intravenous
,
pubmed-meshheading:16510744-Integrin alpha4
,
pubmed-meshheading:16510744-Magnetic Resonance Imaging
,
pubmed-meshheading:16510744-Male
,
pubmed-meshheading:16510744-Middle Aged
,
pubmed-meshheading:16510744-Multiple Sclerosis, Relapsing-Remitting
,
pubmed-meshheading:16510744-Proportional Hazards Models
,
pubmed-meshheading:16510744-Recurrence
pubmed:year
2006
pubmed:articleTitle
A randomized, placebo-controlled trial of natalizumab for relapsing multiple sclerosis.
pubmed:affiliation
Vrije Universiteit Medical Center, Amsterdam, The Netherlands. ch.polman@vumc.nl
pubmed:publicationType
Journal Article
,
Randomized Controlled Trial
,
Research Support, Non-U.S. Gov't
,
Multicenter Study
,
Clinical Trial, Phase III