rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
10
|
pubmed:dateCreated |
2006-5-5
|
pubmed:abstractText |
While processing of MHC class II antigens for presentation to helper T-cells is essential for normal immune response, it is also implicated in the pathogenesis of autoimmune disorders and hypersensitivity reactions. Sequence-based computational techniques for predicting HLA-DQ binding peptides have encountered limited success, with few prediction techniques developed using three-dimensional models.
|
pubmed:grant |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
May
|
pubmed:issn |
1367-4803
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:day |
15
|
pubmed:volume |
22
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1232-8
|
pubmed:dateRevised |
2007-11-14
|
pubmed:meshHeading |
pubmed-meshheading:16510499-Antibodies,
pubmed-meshheading:16510499-Binding Sites,
pubmed-meshheading:16510499-Computer Simulation,
pubmed-meshheading:16510499-Databases, Protein,
pubmed-meshheading:16510499-Epitope Mapping,
pubmed-meshheading:16510499-HLA-DQ Antigens,
pubmed-meshheading:16510499-Immunoassay,
pubmed-meshheading:16510499-Models, Chemical,
pubmed-meshheading:16510499-Models, Immunological,
pubmed-meshheading:16510499-Peptides,
pubmed-meshheading:16510499-Protein Binding,
pubmed-meshheading:16510499-Protein Interaction Mapping,
pubmed-meshheading:16510499-Sequence Analysis, Protein
|
pubmed:year |
2006
|
pubmed:articleTitle |
Prediction of HLA-DQ3.2beta ligands: evidence of multiple registers in class II binding peptides.
|
pubmed:affiliation |
Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore 8 Medical Drive, Singapore 117597, Singapore.
|
pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
|