Source:http://linkedlifedata.com/resource/pubmed/id/16508981
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
3
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pubmed:dateCreated |
2006-3-7
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pubmed:abstractText |
Genetic background and infection have been implicated in the etiology of microscopic polyangiitis (MPA). Killer cell immunoglobulin-like receptors (KIRs) are a diverse family of activating and inhibitory receptors expressed on natural killer (NK) cells and T cells, the genes of which show extreme polymorphism. Some KIRs bind to HLA class I subgroups, and genetic interactions between KIR genes and their ligand HLA have been shown to be associated with several autoimmune and viral diseases. In this study, we examined possible associations of the presence or absence of KIR loci with a genetic predisposition to MPA.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
AIM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:month |
Mar
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pubmed:issn |
0004-3591
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
54
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
992-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16508981-Aged,
pubmed-meshheading:16508981-Female,
pubmed-meshheading:16508981-Genetic Predisposition to Disease,
pubmed-meshheading:16508981-Genotype,
pubmed-meshheading:16508981-Humans,
pubmed-meshheading:16508981-Killer Cells, Natural,
pubmed-meshheading:16508981-Male,
pubmed-meshheading:16508981-Middle Aged,
pubmed-meshheading:16508981-Polymorphism, Genetic,
pubmed-meshheading:16508981-Receptors, Immunologic,
pubmed-meshheading:16508981-Vasculitis
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pubmed:year |
2006
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pubmed:articleTitle |
Association of killer cell immunoglobulin-like receptor genotypes with microscopic polyangiitis.
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pubmed:affiliation |
University of Tokyo, Hongo, Tokyo, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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