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rdf:type |
|
|
lifeskim:mentions |
|
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pubmed:issue |
4
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|
pubmed:dateCreated |
1991-9-12
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|
pubmed:abstractText |
It is hypothesized that Simian Virus 40 (SV40) produces a middle T antigen with a mRNA almost the same size as the small t antigen mRNA and a protein similar in size to that of large T antigen. Both middle T mRNA and protein, therefore, would not be readily discernable. Disruption or removal of the small t antigen translation stop codon by post-transcriptional RNA processing could provide a mechanism to achieve the above. A key role for the small t intron in this process is suggested.
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
IM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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|
pubmed:month |
Apr
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|
pubmed:issn |
0306-9877
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|
pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:volume |
34
|
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pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
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pubmed:pagination |
334-7
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pubmed:dateRevised |
2008-11-21
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pubmed:meshHeading |
pubmed-meshheading:1650882-Animals,
pubmed-meshheading:1650882-Antigens, Polyomavirus Transforming,
pubmed-meshheading:1650882-Cell Transformation, Viral,
pubmed-meshheading:1650882-Codon,
pubmed-meshheading:1650882-Genes, Viral,
pubmed-meshheading:1650882-Introns,
pubmed-meshheading:1650882-RNA, Messenger,
pubmed-meshheading:1650882-RNA, Viral,
pubmed-meshheading:1650882-RNA Splicing,
pubmed-meshheading:1650882-Simian virus 40,
pubmed-meshheading:1650882-Terminator Regions, Genetic,
pubmed-meshheading:1650882-Viral Structural Proteins,
pubmed-meshheading:1650882-Zinc Fingers
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pubmed:year |
1991
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pubmed:articleTitle |
Is there a SV40 middle T antigen?
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pubmed:affiliation |
Department of Medical Biochemistry, University of Cape Town Medical School, South Africa.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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