Linked Life Data

1650788

Source:http://linkedlifedata.com/resource/pubmed/id/1650788

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1991-9-12
pubmed:abstractText
The effects of animal sera used at various concentrations in dilution buffers for radioimmunoassays (RIAs) of human enterovirus-IgM were studied. The origin of the sera had no impact on the titres, but adverse effects on virus-specificity tests were noted when sera from some species were used. In attempts to block the binding of 35S-labelled virus by adding unlabelled virus, sera from cow, horse and lamb and from swine and man could usually not be used; instead of a blocking effect, an increase in bound labelled virus was noted in most cases. When fetal or newborn calf serum or sera from chicken were used, this phenomenon did not occur. The factor(s) causing the enhancement of virus binding could not be identified, but it was evident that it was not present in all sera from the same species and it was very probable that immunoglobulins were not involved.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:issn
0166-0934
pubmed:author
pubmed:issnType
Print
pubmed:volume
31
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
353-8
pubmed:dateRevised
2008-11-21
pubmed:meshHeading
pubmed:articleTitle
Animal serum factor(s) causing adverse effects on RIAs of human enterovirus IgM.
pubmed:affiliation
Department of Medical Virology, Biomedical Centre, University of Uppsala, Sweden.
pubmed:publicationType
Journal Article