rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
5
|
pubmed:dateCreated |
2006-3-1
|
pubmed:abstractText |
Microscopic human cancers can remain dormant for life. Tumor progression depends on sequential events, including a switch to the angiogenic phenotype, i.e., initial recruitment of new vessels. We previously demonstrated that human tumors contain tumor cell populations that are heterogeneous in angiogenic activity. Here, we separated angiogenic from nonangiogenic human tumor cell populations and compared their growth.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Mar
|
pubmed:issn |
1460-2105
|
pubmed:author |
pubmed-author:AkslenLars ALA,
pubmed-author:AlmogNavaN,
pubmed-author:FlynnEvelynE,
pubmed-author:FolkmanJudahJ,
pubmed-author:KangSoo-YoungSY,
pubmed-author:NaumovGeorge NGN,
pubmed-author:SampsonDavidD,
pubmed-author:StraumeOddbjornO,
pubmed-author:TomkinsonHeather AHA,
pubmed-author:WatnickRandolph SRS,
pubmed-author:ZurakowskiDavidD
|
pubmed:issnType |
Electronic
|
pubmed:day |
1
|
pubmed:volume |
98
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
316-25
|
pubmed:dateRevised |
2007-3-13
|
pubmed:meshHeading |
pubmed-meshheading:16507828-Adenocarcinoma,
pubmed-meshheading:16507828-Animals,
pubmed-meshheading:16507828-Cell Line, Tumor,
pubmed-meshheading:16507828-Cell Proliferation,
pubmed-meshheading:16507828-Enzyme-Linked Immunosorbent Assay,
pubmed-meshheading:16507828-Fibroblast Growth Factor 2,
pubmed-meshheading:16507828-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16507828-Glioblastoma,
pubmed-meshheading:16507828-Humans,
pubmed-meshheading:16507828-Immunoblotting,
pubmed-meshheading:16507828-Immunohistochemistry,
pubmed-meshheading:16507828-In Situ Nick-End Labeling,
pubmed-meshheading:16507828-Mice,
pubmed-meshheading:16507828-Mice, SCID,
pubmed-meshheading:16507828-Neovascularization, Pathologic,
pubmed-meshheading:16507828-Osteosarcoma,
pubmed-meshheading:16507828-Phenotype,
pubmed-meshheading:16507828-Thrombospondin 1,
pubmed-meshheading:16507828-Time Factors,
pubmed-meshheading:16507828-Tumor Cells, Cultured,
pubmed-meshheading:16507828-Vascular Endothelial Growth Factor A
|
pubmed:year |
2006
|
pubmed:articleTitle |
A model of human tumor dormancy: an angiogenic switch from the nonangiogenic phenotype.
|
pubmed:affiliation |
Department of Surgery, Children's Hospital, Harvard Medical School, Boston, MA, USA.
|
pubmed:publicationType |
Journal Article,
Research Support, U.S. Gov't, Non-P.H.S.,
Research Support, Non-U.S. Gov't
|