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rdf:type |
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lifeskim:mentions |
umls-concept:C0001675,
umls-concept:C0004083,
umls-concept:C0006370,
umls-concept:C0008902,
umls-concept:C0026882,
umls-concept:C0028754,
umls-concept:C0033105,
umls-concept:C0205082,
umls-concept:C0205245,
umls-concept:C0439849,
umls-concept:C0596170,
umls-concept:C0599755,
umls-concept:C0668289
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pubmed:issue |
5
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pubmed:dateCreated |
2006-5-8
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pubmed:abstractText |
Heterozygous mutations in the melanocortin-4 receptor (MC4R) gene are the most common monogenic form of severe obesity in children. There are conflicting reports regarding the prevalence, nature, and pathogenic effects of MC4R mutations in adults with severe late-onset obesity.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
|
|
pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
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pubmed:month |
May
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pubmed:issn |
0021-972X
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pubmed:author |
pubmed-author:BasdevantArnaudA,
pubmed-author:BertraisSandrineS,
pubmed-author:ClementKarineK,
pubmed-author:DubernBeatriceB,
pubmed-author:HercbergSergeS,
pubmed-author:LacorteJean-MarcJM,
pubmed-author:Lubrano-BerthelierCecileC,
pubmed-author:PicardFranckF,
pubmed-author:ShapiroAstridA,
pubmed-author:VaisseChristianC,
pubmed-author:ZhangSumeiS
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pubmed:issnType |
Print
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pubmed:volume |
91
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pubmed:owner |
NLM
|
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1811-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16507637-Adult,
pubmed-meshheading:16507637-Amino Acid Sequence,
pubmed-meshheading:16507637-Body Mass Index,
pubmed-meshheading:16507637-Cohort Studies,
pubmed-meshheading:16507637-DNA,
pubmed-meshheading:16507637-Eating Disorders,
pubmed-meshheading:16507637-Female,
pubmed-meshheading:16507637-Gene Frequency,
pubmed-meshheading:16507637-Genotype,
pubmed-meshheading:16507637-Heterozygote,
pubmed-meshheading:16507637-Humans,
pubmed-meshheading:16507637-Male,
pubmed-meshheading:16507637-Middle Aged,
pubmed-meshheading:16507637-Molecular Sequence Data,
pubmed-meshheading:16507637-Mutation,
pubmed-meshheading:16507637-Obesity,
pubmed-meshheading:16507637-Phenotype,
pubmed-meshheading:16507637-Prospective Studies,
pubmed-meshheading:16507637-Receptor, Melanocortin, Type 4,
pubmed-meshheading:16507637-Receptors, Cell Surface,
pubmed-meshheading:16507637-Reverse Transcriptase Polymerase Chain Reaction,
pubmed-meshheading:16507637-alpha-MSH
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pubmed:year |
2006
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pubmed:articleTitle |
Melanocortin 4 receptor mutations in a large cohort of severely obese adults: prevalence, functional classification, genotype-phenotype relationship, and lack of association with binge eating.
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pubmed:affiliation |
Diabetes Center and Department of Medicine, University of California San Francisco, San Francisco, California 94143-0573, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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