Linked Life Data

1650703

Source:http://linkedlifedata.com/resource/pubmed/id/1650703

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
2-3
pubmed:dateCreated
1991-9-10
pubmed:abstractText
Guinea-pig trachea possesses an inhibitory (bronchodilator) non-adrenergic, non-cholinergic (i-NANC) innervation associated with cholinergic nerves, which may be mediated, at least in part, by nitric oxide (NO). L-NG-Nitro-arginine methyl ester (L-NAME), an inhibitor of endogenous NO synthesis, enhanced cholinergic responses to electrical field stimulation with no effect on contractile responses to exogenous acetylcholine or excitatory NANC (e-NANC) bronchoconstriction. The effects of L-NAME were reversed by L-arginine but not D-arginine. These results suggest that NO released by nerve stimulation modulates cholinergic neurotransmission in guinea-pig trachea.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Jun
pubmed:issn
0014-2999
pubmed:author
pubmed:issnType
Print
pubmed:day
6
pubmed:volume
198
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
219-21
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
1991
pubmed:articleTitle
Nitric oxide as an endogenous modulator of cholinergic neurotransmission in guinea-pig airways.
pubmed:affiliation
Department of Thoracic Medicine, National Heart and Lung Institute, Chelsea, London, U.K.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't