Linked Life Data

16506311

Source:http://linkedlifedata.com/resource/pubmed/id/16506311

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
4
pubmed:dateCreated
2006-2-27
pubmed:abstractText
Among the ABC transporters, the pleiotropic drug resistance (PDR) family is particular in that its members are found only in fungi and plants and have a reverse domain organization, i.e., the nucleotide binding domain precedes the transmembrane domain. In Arabidopsis and rice, for which the full genome has been sequenced, the family of plant ABC transporters contains 15 and 23 PDR genes, respectively, which can be tentatively organized using the sequence data into five subfamilies. Most of the plant PDR genes so far characterized belong to subfamily I and have been shown to be involved in responses to abiotic and biotic stress, in the latter case, probably by transporting antimicrobial secondary metabolites to the cell surface. Only a single subfamily II member has been characterized. Induction of its expression by iron deficiency suggests its involvement in iron deficiency stress, thus, enlightening a new physiological role for a PDR gene.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Feb
pubmed:issn
0014-5793
pubmed:author
pubmed:issnType
Print
pubmed:day
13
pubmed:volume
580
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
1123-30
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Organization and function of the plant pleiotropic drug resistance ABC transporter family.
pubmed:affiliation
Unité de Biochimie Physiologique, Institut des Sciences de la Vie, Univerisity of Louvain, Croix du Sud 5-15, 1348 Louvain-la-Neuve, Belgium.
pubmed:publicationType
Journal Article, Review