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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-2-28
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pubmed:abstractText |
Defects of the ubiquitin-proteasome (UP) system, a multicatalytic complex degrading polyubiquitinated proteins, may intervene in the pathogenesis of neurodegenerative disorders characterized by intracellular formation of protein aggregates such as Parkinson disease (PD) and Alzheimer disease (AD) by inducing proapoptotic conditions.
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1526-632X
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pubmed:author |
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pubmed:issnType |
Electronic
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pubmed:day |
28
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
529-34
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16505307-Aged,
pubmed-meshheading:16505307-Alzheimer Disease,
pubmed-meshheading:16505307-Antiparkinson Agents,
pubmed-meshheading:16505307-Caspase 3,
pubmed-meshheading:16505307-Caspase 9,
pubmed-meshheading:16505307-Caspases,
pubmed-meshheading:16505307-Female,
pubmed-meshheading:16505307-Humans,
pubmed-meshheading:16505307-Lymphocytes,
pubmed-meshheading:16505307-Male,
pubmed-meshheading:16505307-Middle Aged,
pubmed-meshheading:16505307-Parkinson Disease,
pubmed-meshheading:16505307-Proteasome Endopeptidase Complex,
pubmed-meshheading:16505307-Reference Values
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pubmed:year |
2006
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pubmed:articleTitle |
Peripheral proteasome and caspase activity in Parkinson disease and Alzheimer disease.
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pubmed:affiliation |
Laboratory of Functional Neurochemistry, IRCCS Neurological Institute C. Mondino, Pavia, Italy. fabio.blandini@mondino.it
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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