Source:http://linkedlifedata.com/resource/pubmed/id/16504726
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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
2006-2-28
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pubmed:abstractText |
Islet cell transplantation is a promising method to restore insulin independence to patients with type 1 diabetes mellitus. A main problem in clinical islet transplantation is the fact that only a small percentage of allogeneic islet-transplanted type 1 diabetic patients can completely omit insulin injections after transplantation. One reason for the impaired survival of islet grafts is aberration of the function of islets due to toxic agents, including oxygen radicals and nitric oxide, which arise during warm or cold ischemic time. Therefore, in clinical islet transplantation, islets have been preserved with a mixture of antioxidants to reduce free radical-mediated damage of transplanted beta cells. Our aim was to examine hepatic tissue after metabolic normalization following intraportal islet transplantation after application of sulforaphane.
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pubmed:commentsCorrections | |
pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Anticarcinogenic Agents,
http://linkedlifedata.com/resource/pubmed/chemical/Glucagon,
http://linkedlifedata.com/resource/pubmed/chemical/Insulin,
http://linkedlifedata.com/resource/pubmed/chemical/Thiocyanates,
http://linkedlifedata.com/resource/pubmed/chemical/sulforafan
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pubmed:status |
MEDLINE
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pubmed:issn |
0041-1345
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
38
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
282-3
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pubmed:dateRevised |
2011-11-17
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pubmed:meshHeading |
pubmed-meshheading:16504726-Animals,
pubmed-meshheading:16504726-Anticarcinogenic Agents,
pubmed-meshheading:16504726-Diabetes Mellitus, Experimental,
pubmed-meshheading:16504726-Disease Models, Animal,
pubmed-meshheading:16504726-Glucagon,
pubmed-meshheading:16504726-Immunohistochemistry,
pubmed-meshheading:16504726-Insulin,
pubmed-meshheading:16504726-Islets of Langerhans,
pubmed-meshheading:16504726-Islets of Langerhans Transplantation,
pubmed-meshheading:16504726-Liver,
pubmed-meshheading:16504726-Male,
pubmed-meshheading:16504726-Portal Vein,
pubmed-meshheading:16504726-Rats,
pubmed-meshheading:16504726-Rats, Inbred Strains,
pubmed-meshheading:16504726-Thiocyanates
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pubmed:articleTitle |
Application of sulforaphane: histopathological study of intraportal transplanted pancreatic islets into livers of diabetic rats.
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pubmed:affiliation |
Department of General and Transplant Surgery, Warsaw Medical University, ul. Nowogrodzka 59, 02-006 Warsaw, Poland. ewa-solowiej@wp.pl
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pubmed:publicationType |
Journal Article,
Retracted Publication
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