| pubmed-article:16504351 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C0011306 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C2266975 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C0041904 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C0542341 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C1332714 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C1336634 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C0162493 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C0449450 | lld:lifeskim |
| pubmed-article:16504351 | lifeskim:mentions | umls-concept:C2349975 | lld:lifeskim |
| pubmed-article:16504351 | pubmed:issue | 16 | lld:pubmed |
| pubmed-article:16504351 | pubmed:dateCreated | 2006-3-27 | lld:pubmed |
| pubmed-article:16504351 | pubmed:abstractText | In vitro immunization with HCV lipopeptide aa 20-44 results in antigen-specific T cells. Here, we studied whether presentation of the lipopeptide by dendritic cells (DC) results in enhanced T cell functions. DC-immunized T cells showed significantly augmented proliferation and IFN-gamma secretion upon HCV-specific re-stimulation. This effect was related to significantly increased expression of TLR2 on DC-immunized CD4+ T cells and required TLR2 triggering during re-stimulation. In contrast, numbers of HLA-A2-pentamer-positive CD8+ T cells and granzyme B-secreting T cells remained unchanged. Thus, up-regulation of TLR2 during immunization with DC enhances functions of CD4+ T cells but not CD8+ T cells. | lld:pubmed |
| pubmed-article:16504351 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16504351 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504351 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16504351 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:16504351 | pubmed:issn | 0264-410X | lld:pubmed |
| pubmed-article:16504351 | pubmed:author | pubmed-author:SauerbruchTil... | lld:pubmed |
| pubmed-article:16504351 | pubmed:author | pubmed-author:SpenglerUlric... | lld:pubmed |
| pubmed-article:16504351 | pubmed:author | pubmed-author:NattermannJac... | lld:pubmed |
| pubmed-article:16504351 | pubmed:author | pubmed-author:NischalkeHans... | lld:pubmed |
| pubmed-article:16504351 | pubmed:author | pubmed-author:LanghansBetti... | lld:pubmed |
| pubmed-article:16504351 | pubmed:author | pubmed-author:Braunschweige... | lld:pubmed |
| pubmed-article:16504351 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16504351 | pubmed:day | 12 | lld:pubmed |
| pubmed-article:16504351 | pubmed:volume | 24 | lld:pubmed |
| pubmed-article:16504351 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16504351 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16504351 | pubmed:pagination | 3066-75 | lld:pubmed |
| pubmed-article:16504351 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
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| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
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| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:meshHeading | pubmed-meshheading:16504351... | lld:pubmed |
| pubmed-article:16504351 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16504351 | pubmed:articleTitle | Presentation of the HCV-derived lipopeptide LP20-44 by dendritic cells enhances function of in vitro-generated CD4+ T cells via up-regulation of TLR2. | lld:pubmed |
| pubmed-article:16504351 | pubmed:affiliation | Department of Internal Medicine I, University of Bonn, Sigmund-Freud-Strasse 25, 53105 Bonn, Germany. bettina.langhans@ukb.uni-bonn.de | lld:pubmed |
| pubmed-article:16504351 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16504351 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16504351 | lld:pubmed |
