| pubmed-article:16504025 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16504025 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:16504025 | lifeskim:mentions | umls-concept:C0012634 | lld:lifeskim |
| pubmed-article:16504025 | lifeskim:mentions | umls-concept:C0162340 | lld:lifeskim |
| pubmed-article:16504025 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:16504025 | lifeskim:mentions | umls-concept:C1334046 | lld:lifeskim |
| pubmed-article:16504025 | pubmed:dateCreated | 2006-3-13 | lld:pubmed |
| pubmed-article:16504025 | pubmed:abstractText | Several studies have compared various features of heritable disease genes with other so called non-disease genes, but they have yielded some conflicting results. A potential problem in those studies is that the non-disease genes contained a large number of essential genes--genes which are indispensable for humans to survive and reproduce. Since a functional disruption of an essential gene has fatal consequences, it's more reasonable to regard essential genes as extremely severe "disease" genes. Here we perform a comparative study on the features of human essential, disease, and other genes. | lld:pubmed |
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| pubmed-article:16504025 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16504025 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16504025 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:16504025 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16504025 | pubmed:issn | 1471-2164 | lld:pubmed |
| pubmed-article:16504025 | pubmed:author | pubmed-author:ZhouXianghong... | lld:pubmed |
| pubmed-article:16504025 | pubmed:author | pubmed-author:WangLiL | lld:pubmed |
| pubmed-article:16504025 | pubmed:author | pubmed-author:LANVV | lld:pubmed |
| pubmed-article:16504025 | pubmed:author | pubmed-author:ChenTingT | lld:pubmed |
| pubmed-article:16504025 | pubmed:author | pubmed-author:SunFengzhuF | lld:pubmed |
| pubmed-article:16504025 | pubmed:author | pubmed-author:TuZhidongZ | lld:pubmed |
| pubmed-article:16504025 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:16504025 | pubmed:volume | 7 | lld:pubmed |
| pubmed-article:16504025 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16504025 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16504025 | pubmed:pagination | 31 | lld:pubmed |
| pubmed-article:16504025 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:16504025 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16504025 | pubmed:articleTitle | Further understanding human disease genes by comparing with housekeeping genes and other genes. | lld:pubmed |
| pubmed-article:16504025 | pubmed:affiliation | Molecular and Computational Biology Program, University of Southern California, Los Angeles, California 90089, USA. ztu@usc.edu | lld:pubmed |
| pubmed-article:16504025 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16504025 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:16504025 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
| pubmed-article:16504025 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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