Linked Life Data

16500054

Source:http://linkedlifedata.com/resource/pubmed/id/16500054

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1-2
pubmed:dateCreated
2006-3-20
pubmed:abstractText
Different scattering methods were used as tools to assess the size of droplets in highly diluted microemulsions. These were obtained after dilution of a self-emulsifying system made up of an oil, a surfactant and ethanol. Typical methods, often used in size and shape determination of particles, such as SAXS and USAXS suffer in the present case from a lack of electrondensity contrast. It becomes clear from our extensive use of dynamic light scattering that one should be careful in interpreting the latter data as well. Sample preparation and the subsequent handling of the samples during the experiments strongly affect reproducibility of the results. There is a need for well-defined protocols at the level of sample preparation and data handling. In the present research one uses extensively dynamic light scattering (DLS) in the back scattering mode and strengths and pitfalls, inherent to the backscattering technique, are discussed. It is crucial to be aware of droplet size distributions (monomodal/bimodal/multimodal) while reporting mean radii (Rh) as this radius is only relevant in the case of well-defined monomodal distributions. Moreover, one should asses the shape of the droplets prior to data interpretation, as usual in scattering methods, by an independent method. Anyway the shape of the time correlation functions of the scattered intensity should be reported or at least inspected as they provide information on the reproducibility of the experiments hence safegarding the value of the physical meaning of the final value of droplet size (Rh). Preferentially static light scattering (SLS) measurements should always support DLS experiments as the angular dependence is very sensitive to the presence of large particles.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Apr
pubmed:issn
0378-5173
pubmed:author
pubmed:issnType
Print
pubmed:day
7
pubmed:volume
312
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
187-95
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Light scattering measurements on microemulsions: estimation of droplet sizes.
pubmed:affiliation
Laboratory of Pharmacotechnology and Biopharmacy, Catholic University of Leuven, Herestraat 49, B-3000 Leuven, Belgium.
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't