Source:http://linkedlifedata.com/resource/pubmed/id/16498459
Switch to
Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
2
|
pubmed:dateCreated |
2006-2-24
|
pubmed:abstractText |
Highly repetitive DNA sequences constitute a significant portion of most eukaryotic genomes, raising questions about their evolutionary origins and amplification dynamics. In this study, a novel chicken repetitive DNA family, the HinfI repeat, was characterized. The basic repeating unit of this family displays a uniform length of 770 bp, which was defined by the recognition site of HinfI. The HinfI repeat was specifically localized in the pericentric region of chromosome 4 by fluorescence in situ hybridization and constitutes 0.51% of the chicken genome. Interestingly, a chicken repeat 1 (CR1) element has been identified within this basic repeating unit. Like other CR1 elements, this CR1 element also displays typical retrotransposition characteristics, including a highly conserved 3' region and a badly truncated 5' end. This direct evidence from sequence analysis, together with our Southern blot results, suggests that the HinfI repeat may originate from a unique region containing a retrotransposed CR1 element.
|
pubmed:language |
eng
|
pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Feb
|
pubmed:issn |
0831-2796
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
49
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
97-103
|
pubmed:dateRevised |
2008-8-29
|
pubmed:meshHeading |
pubmed-meshheading:16498459-Animals,
pubmed-meshheading:16498459-Base Sequence,
pubmed-meshheading:16498459-Chickens,
pubmed-meshheading:16498459-Deoxyribonucleases, Type II Site-Specific,
pubmed-meshheading:16498459-Genome,
pubmed-meshheading:16498459-In Situ Hybridization, Fluorescence,
pubmed-meshheading:16498459-Models, Genetic,
pubmed-meshheading:16498459-Molecular Sequence Data,
pubmed-meshheading:16498459-Retroelements,
pubmed-meshheading:16498459-Sequence Analysis, DNA,
pubmed-meshheading:16498459-Sequence Homology, Nucleic Acid,
pubmed-meshheading:16498459-Tandem Repeat Sequences
|
pubmed:year |
2006
|
pubmed:articleTitle |
A CR1 element is embedded in a novel tandem repeat (HinfI repeat) within the chicken genome.
|
pubmed:affiliation |
Department of Zoology, The University of Hong Kong, Hong kong SAR, China.
|
pubmed:publicationType |
Journal Article
|