rdf:type |
|
lifeskim:mentions |
umls-concept:C0013931,
umls-concept:C0038454,
umls-concept:C0040017,
umls-concept:C0087111,
umls-concept:C0205412,
umls-concept:C0231242,
umls-concept:C0288672,
umls-concept:C0871261,
umls-concept:C0917996,
umls-concept:C1704632,
umls-concept:C1705946,
umls-concept:C1706817,
umls-concept:C2911692
|
pubmed:issue |
1
|
pubmed:dateCreated |
2006-2-24
|
pubmed:abstractText |
Thromboembolic stroke is the most common severe complication following coil embolization of intracerebral aneurysms, with a 5% incidence of permanent deficits. Despite heparin anticoagulation, rescue therapy with the platelet glycoprotein IIb/IIIa receptor antagonist abciximab may be required. However, we describe a failure of abciximab rescue therapy and discuss the importance of monitoring the variable individual response to abciximab.
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:issn |
1541-6933
|
pubmed:author |
|
pubmed:issnType |
Print
|
pubmed:volume |
4
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
32-4
|
pubmed:dateRevised |
2007-11-15
|
pubmed:meshHeading |
pubmed-meshheading:16498193-Aged,
pubmed-meshheading:16498193-Aged, 80 and over,
pubmed-meshheading:16498193-Antibodies, Monoclonal,
pubmed-meshheading:16498193-Embolization, Therapeutic,
pubmed-meshheading:16498193-Female,
pubmed-meshheading:16498193-Humans,
pubmed-meshheading:16498193-Immunoglobulin Fab Fragments,
pubmed-meshheading:16498193-Intracranial Aneurysm,
pubmed-meshheading:16498193-Platelet Aggregation Inhibitors,
pubmed-meshheading:16498193-Stents,
pubmed-meshheading:16498193-Stroke,
pubmed-meshheading:16498193-Thrombelastography,
pubmed-meshheading:16498193-Treatment Failure
|
pubmed:year |
2006
|
pubmed:articleTitle |
Thromboelastography detects inadequate response to abciximab therapy during stent-assisted cerebral aneurysm coil embolization complicated by stroke.
|
pubmed:affiliation |
Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA. lombar004@mc.duke.edu
|
pubmed:publicationType |
Journal Article,
Case Reports
|