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Predicate | Object |
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rdf:type | |
lifeskim:mentions | |
pubmed:issue |
1
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pubmed:dateCreated |
1991-8-23
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pubmed:abstractText |
Determining the cause of Cushing's disease and correcting the abnormality presents a continuing challenge to the clinician despite remarkable advances in diagnostic and therapeutic techniques. We present seven cases to illustrate 1) the classic disorder cured by pituitary adenomectomy; 2) persistence of the disease after adenomectomy; 3) Cushing's disease manifesting in the puerperium and remitting with dopamine agonist therapy; 4) a patient whose disease relapsed at least five times during 20 years of treatment by adrenalectomy, pituitary radiation, mitotane, and pituitary adenomectomy; 5) the Nelson syndrome; 6) the ectopic adrenocorticotropic hormone (ACTH) syndrome in a patient with dexamethasone suppressible urinary cortisol who had a pituitary adenoma which stained positively for ACTH but who was not cured by total hypophysectomy; and 7) a patient whose ACTH-secreting tumor proved fatal despite repeated surgical, radiologic and pharmacologic measures.
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pubmed:language |
eng
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pubmed:journal | |
pubmed:citationSubset |
IM
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pubmed:chemical | |
pubmed:status |
MEDLINE
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pubmed:issn |
0018-0416
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pubmed:author | |
pubmed:issnType |
Print
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pubmed:volume |
39
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
10-7
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1649807-Adrenocorticotropic Hormone,
pubmed-meshheading:1649807-Adult,
pubmed-meshheading:1649807-Aged,
pubmed-meshheading:1649807-Cushing Syndrome,
pubmed-meshheading:1649807-Female,
pubmed-meshheading:1649807-Humans,
pubmed-meshheading:1649807-Hypophysectomy,
pubmed-meshheading:1649807-Male,
pubmed-meshheading:1649807-Nelson Syndrome,
pubmed-meshheading:1649807-Puerperal Disorders,
pubmed-meshheading:1649807-Recurrence
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pubmed:year |
1991
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pubmed:articleTitle |
Cushing's disease: dilemmas of diagnosis and management.
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pubmed:affiliation |
Division of Endocrinology and Metabolism, Henry Ford Hospital, Detroit, MI 48202.
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pubmed:publicationType |
Journal Article,
Case Reports
|