rdf:type |
|
lifeskim:mentions |
|
pubmed:issue |
4
|
pubmed:dateCreated |
2006-4-25
|
pubmed:abstractText |
Proton pump inhibitors reduce ulcer recurrence in non-steroidal anti-inflammatory drug (NSAID) users, but their impact in at-risk ulcer-free patients using the current spectrum of prescribed agents has not been clearly defined. We assessed esomeprazole for ulcer prevention in at-risk patients (> or = 60 yr and/or ulcer history) taking NSAIDs, including COX-2 inhibitors. Such studies are particularly relevant, given that concerns regarding adverse cardiovascular outcomes among COX-2 inhibitor users may prompt re-evaluation of their use.
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pubmed:commentsCorrections |
|
pubmed:language |
eng
|
pubmed:journal |
|
pubmed:citationSubset |
IM
|
pubmed:chemical |
|
pubmed:status |
MEDLINE
|
pubmed:month |
Apr
|
pubmed:issn |
0002-9270
|
pubmed:author |
pubmed-author:AhlbomHenrikH,
pubmed-author:ChanFrancis K LFK,
pubmed-author:HawkeyChristopherC,
pubmed-author:KleczkowskiDariuszD,
pubmed-author:NaesdalJørgenJ,
pubmed-author:RainoldiJorge LJL,
pubmed-author:ScheimanJames MJM,
pubmed-author:SzczepanskiLeszekL,
pubmed-author:TalleyNicholas JNJ,
pubmed-author:TulassayZsoltZ,
pubmed-author:UngKjell-ArneKA,
pubmed-author:VakilNimishN,
pubmed-author:YeomansNeville DND
|
pubmed:issnType |
Print
|
pubmed:volume |
101
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
701-10
|
pubmed:dateRevised |
2006-11-15
|
pubmed:meshHeading |
pubmed-meshheading:16494585-Aged,
pubmed-meshheading:16494585-Anti-Inflammatory Agents, Non-Steroidal,
pubmed-meshheading:16494585-Anti-Ulcer Agents,
pubmed-meshheading:16494585-Arthritis, Rheumatoid,
pubmed-meshheading:16494585-Cyclooxygenase 2 Inhibitors,
pubmed-meshheading:16494585-Double-Blind Method,
pubmed-meshheading:16494585-Duodenal Ulcer,
pubmed-meshheading:16494585-Female,
pubmed-meshheading:16494585-Humans,
pubmed-meshheading:16494585-Male,
pubmed-meshheading:16494585-Middle Aged,
pubmed-meshheading:16494585-Omeprazole,
pubmed-meshheading:16494585-Osteoarthritis,
pubmed-meshheading:16494585-Proton Pumps,
pubmed-meshheading:16494585-Risk Factors,
pubmed-meshheading:16494585-Stomach Ulcer
|
pubmed:year |
2006
|
pubmed:articleTitle |
Prevention of ulcers by esomeprazole in at-risk patients using non-selective NSAIDs and COX-2 inhibitors.
|
pubmed:affiliation |
Division of Gastroenterology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, USA.
|
pubmed:publicationType |
Journal Article,
Randomized Controlled Trial,
Research Support, Non-U.S. Gov't,
Multicenter Study
|