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rdf:type |
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|
lifeskim:mentions |
|
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pubmed:issue |
8
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pubmed:dateCreated |
2006-4-27
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pubmed:abstractText |
Conjugated linoleic acids (CLAs) have anti-tumorigenic properties in animal models and anti-proliferative effects on cancer cells in vitro. Previous studies have shown that the NF-kappaB pathway is involved regulating anti-apoptotic gene expression. The present study investigated the effects of CLAs (cis-9, trans-11, and trans-10, cis-12 isomers and a 50:50 mixture) on apoptosis and NF-kappaB activation in LNCaP cells.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Jun
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pubmed:issn |
0270-4137
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:day |
1
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pubmed:volume |
66
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
839-46
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16491481-Annexin A5,
pubmed-meshheading:16491481-Apoptosis,
pubmed-meshheading:16491481-Cell Line, Tumor,
pubmed-meshheading:16491481-DNA, Neoplasm,
pubmed-meshheading:16491481-Electrophoretic Mobility Shift Assay,
pubmed-meshheading:16491481-Flow Cytometry,
pubmed-meshheading:16491481-Humans,
pubmed-meshheading:16491481-I-kappa B Proteins,
pubmed-meshheading:16491481-Isomerism,
pubmed-meshheading:16491481-Linoleic Acids, Conjugated,
pubmed-meshheading:16491481-Male,
pubmed-meshheading:16491481-NF-kappa B,
pubmed-meshheading:16491481-Phosphorylation,
pubmed-meshheading:16491481-Prostatic Neoplasms,
pubmed-meshheading:16491481-Transcription, Genetic,
pubmed-meshheading:16491481-Tumor Necrosis Factor-alpha
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pubmed:year |
2006
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pubmed:articleTitle |
Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid.
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pubmed:affiliation |
The Robert Gordon University, School of Life Sciences, St. Andrews Street, Aberdeen, United Kingdom.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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