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rdf:type |
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lifeskim:mentions |
umls-concept:C0035647,
umls-concept:C0035668,
umls-concept:C0036525,
umls-concept:C0069676,
umls-concept:C0086022,
umls-concept:C0086418,
umls-concept:C0205263,
umls-concept:C0279626,
umls-concept:C0392756,
umls-concept:C0442335,
umls-concept:C1515655,
umls-concept:C1522484,
umls-concept:C1533691,
umls-concept:C1705099
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pubmed:issue |
4
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pubmed:dateCreated |
2006-2-20
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pubmed:abstractText |
To elucidate the clinical significance of osteopontin and the effect of conditional down-regulation of osteopontin in esophageal squamous cell carcinoma (ESCC), we investigated osteopontin expression in tumors and tested an inducible osteopontin-short-hairpin RNA (shRNA) expression vector in an ESCC cell line.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
http://linkedlifedata.com/resource/pubmed/chemical/Doxycycline,
http://linkedlifedata.com/resource/pubmed/chemical/Osteopontin,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Messenger,
http://linkedlifedata.com/resource/pubmed/chemical/RNA, Small Interfering,
http://linkedlifedata.com/resource/pubmed/chemical/SPP1 protein, human,
http://linkedlifedata.com/resource/pubmed/chemical/Sialoglycoproteins,
http://linkedlifedata.com/resource/pubmed/chemical/Spp1 protein, mouse
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1078-0432
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pubmed:author |
|
|
pubmed:issnType |
Print
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pubmed:day |
15
|
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pubmed:volume |
12
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1308-16
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16489088-Administration, Oral,
pubmed-meshheading:16489088-Adult,
pubmed-meshheading:16489088-Aged,
pubmed-meshheading:16489088-Aged, 80 and over,
pubmed-meshheading:16489088-Animals,
pubmed-meshheading:16489088-Base Sequence,
pubmed-meshheading:16489088-Carcinoma, Squamous Cell,
pubmed-meshheading:16489088-Cell Line, Tumor,
pubmed-meshheading:16489088-Cell Movement,
pubmed-meshheading:16489088-Cell Proliferation,
pubmed-meshheading:16489088-Doxycycline,
pubmed-meshheading:16489088-Esophageal Neoplasms,
pubmed-meshheading:16489088-Female,
pubmed-meshheading:16489088-Gene Expression Regulation, Neoplastic,
pubmed-meshheading:16489088-Genetic Vectors,
pubmed-meshheading:16489088-Humans,
pubmed-meshheading:16489088-Lymphatic Metastasis,
pubmed-meshheading:16489088-Male,
pubmed-meshheading:16489088-Mice,
pubmed-meshheading:16489088-Mice, Inbred BALB C,
pubmed-meshheading:16489088-Mice, Nude,
pubmed-meshheading:16489088-Middle Aged,
pubmed-meshheading:16489088-Molecular Sequence Data,
pubmed-meshheading:16489088-Neoplasms, Experimental,
pubmed-meshheading:16489088-Oligonucleotide Array Sequence Analysis,
pubmed-meshheading:16489088-Osteopontin,
pubmed-meshheading:16489088-RNA, Messenger,
pubmed-meshheading:16489088-RNA, Small Interfering,
pubmed-meshheading:16489088-Sialoglycoproteins,
pubmed-meshheading:16489088-Transfection
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pubmed:year |
2006
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pubmed:articleTitle |
An inducible short-hairpin RNA vector against osteopontin reduces metastatic potential of human esophageal squamous cell carcinoma in vitro and in vivo.
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pubmed:affiliation |
Department of Surgery and Surgical Basic Science, Graduate School of Medicine, Kyoto University, Kyoto, Japan.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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