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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-2-20
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pubmed:abstractText |
Hepatocyte growth factor (HGF) and its receptor Met are involved in the initiation, progression, and metastasis of numerous systemic and central nervous system tumors. Thus, an anti-HGF monoclonal antibody (mAb) capable of blocking the HGF-Met interaction could have broad applicability in cancer therapy.
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pubmed:grant |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
IM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
1078-0432
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pubmed:author |
|
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pubmed:issnType |
Print
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pubmed:day |
15
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pubmed:volume |
12
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1292-8
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16489086-Animals,
pubmed-meshheading:16489086-Antibodies, Monoclonal,
pubmed-meshheading:16489086-Apoptosis,
pubmed-meshheading:16489086-Brain Neoplasms,
pubmed-meshheading:16489086-Cell Line,
pubmed-meshheading:16489086-Cell Line, Tumor,
pubmed-meshheading:16489086-Cell Proliferation,
pubmed-meshheading:16489086-Dose-Response Relationship, Drug,
pubmed-meshheading:16489086-Endothelial Cells,
pubmed-meshheading:16489086-Female,
pubmed-meshheading:16489086-Glioma,
pubmed-meshheading:16489086-Hepatocyte Growth Factor,
pubmed-meshheading:16489086-Humans,
pubmed-meshheading:16489086-Mice,
pubmed-meshheading:16489086-Mice, Inbred BALB C,
pubmed-meshheading:16489086-Mice, Nude,
pubmed-meshheading:16489086-Mice, SCID,
pubmed-meshheading:16489086-Neutralization Tests,
pubmed-meshheading:16489086-Remission Induction,
pubmed-meshheading:16489086-Time Factors,
pubmed-meshheading:16489086-Xenograft Model Antitumor Assays
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pubmed:year |
2006
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pubmed:articleTitle |
Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts.
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pubmed:affiliation |
Galaxy Biotech, LLC, Mountain View, California 94033, USA. kjinkim@msn.com
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pubmed:publicationType |
Journal Article,
Research Support, N.I.H., Extramural
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