|
rdf:type |
|
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lifeskim:mentions |
umls-concept:C0031716,
umls-concept:C0040018,
umls-concept:C0282440,
umls-concept:C0524727,
umls-concept:C1096777,
umls-concept:C1522408,
umls-concept:C1522492,
umls-concept:C1549649,
umls-concept:C1697272,
umls-concept:C1704806,
umls-concept:C2349209
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pubmed:issue |
3
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|
pubmed:dateCreated |
2006-2-20
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|
pubmed:abstractText |
During cardiopulmonary bypass, blood contact with the large nonendothelial surfaces of the extracorporeal circuit induces activation and consumption of platelets and plasma coagulation factors. Phosphorylcholine (Pc) coating of oxygenators has been designed to improve surface biocompatibility. We evaluated the effects of a Pc-coated oxygenator on blood coagulation in patients undergoing high-risk open heart surgery and receiving tranexamic acid.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
|
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pubmed:status |
MEDLINE
|
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pubmed:month |
Mar
|
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pubmed:issn |
1552-6259
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|
pubmed:author |
|
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pubmed:issnType |
Electronic
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pubmed:volume |
81
|
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
886-91
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16488689-Aged,
pubmed-meshheading:16488689-Antifibrinolytic Agents,
pubmed-meshheading:16488689-Biocompatible Materials,
pubmed-meshheading:16488689-Blood Loss, Surgical,
pubmed-meshheading:16488689-Blood Transfusion,
pubmed-meshheading:16488689-Cardiopulmonary Bypass,
pubmed-meshheading:16488689-Extracorporeal Circulation,
pubmed-meshheading:16488689-Female,
pubmed-meshheading:16488689-Hemostatics,
pubmed-meshheading:16488689-Humans,
pubmed-meshheading:16488689-Intraoperative Period,
pubmed-meshheading:16488689-Male,
pubmed-meshheading:16488689-Middle Aged,
pubmed-meshheading:16488689-Phosphorylcholine,
pubmed-meshheading:16488689-Platelet Count,
pubmed-meshheading:16488689-Reoperation,
pubmed-meshheading:16488689-Treatment Outcome
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pubmed:year |
2006
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pubmed:articleTitle |
Phosphorylcholine coating may limit thrombin formation during high-risk cardiac surgery: a randomized controlled trial.
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pubmed:affiliation |
Department of Cardiovascular Anesthesia and Intensive Care, IRCCS San Raffaele Hospital, Milan, Italy. pappalardo.federico@hsr.it
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pubmed:publicationType |
Journal Article,
Comparative Study,
Randomized Controlled Trial
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