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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
4
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pubmed:dateCreated |
2006-3-21
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pubmed:abstractText |
Hemorrhagic shock and resuscitation trigger a global ischemia/reperfusion phenomenon, in which various inflammatory processes critically contribute to the ensuing tissue damage. Adenosine is an endogenous nucleoside that is released during shock. Activation of adenosine A(2A) receptors can broadly inactivate inflammatory cascades. The current study was designed to evaluate the effect of A(2A) receptor activation on organ injury and inflammation in the setting of global ischemia/reperfusion elicited by trauma/hemorrhagic shock and resuscitation.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Apr
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pubmed:issn |
0090-3493
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
34
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
1119-25
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pubmed:dateRevised |
2010-11-18
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pubmed:meshHeading |
pubmed-meshheading:16484904-Adenosine,
pubmed-meshheading:16484904-Adenosine A2 Receptor Agonists,
pubmed-meshheading:16484904-Animals,
pubmed-meshheading:16484904-Inflammation,
pubmed-meshheading:16484904-Lung Diseases,
pubmed-meshheading:16484904-Male,
pubmed-meshheading:16484904-Phenethylamines,
pubmed-meshheading:16484904-Rats,
pubmed-meshheading:16484904-Rats, Sprague-Dawley,
pubmed-meshheading:16484904-Receptor, Adenosine A2A,
pubmed-meshheading:16484904-Reperfusion Injury,
pubmed-meshheading:16484904-Resuscitation,
pubmed-meshheading:16484904-Shock, Hemorrhagic,
pubmed-meshheading:16484904-Shock, Traumatic
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pubmed:year |
2006
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pubmed:articleTitle |
Adenosine A2A receptor activation reduces lung injury in trauma/hemorrhagic shock.
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pubmed:affiliation |
Department of Surgery, UMDNJ-New Jersey Medical School, Newark, USA.
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pubmed:publicationType |
Journal Article,
Comment,
Research Support, N.I.H., Extramural
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