Linked Life Data

16483269

Source:http://linkedlifedata.com/resource/pubmed/id/16483269

Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:dateCreated
2006-2-17
pubmed:abstractText
Gastro-oesophageal reflux disease is associated with several extraoesophageal disease states including laryngitis, asthma, chronic cough and non-cardiac chest pain. Currently, the exact role reflux of gastric contents play in the pathogenesis of extraoesophageal symptoms remain controversial. Twenty-four hours pH monitoring is often considered the 'gold standard' in the diagnosis of gastro-oesophageal reflux disease and is increasingly utilized in patients with extraoesophageal symptoms. The use of this test is aimed at improving the association between patients' extraoesophageal symptoms and oesophageal or hypopharyngeal acid reflux events. However, the clinical utility of pH monitoring in this patient population remains controversial. Important clinical questions in this area include: does the presence of abnormal oesophageal acid reflux suggest a causal association between patients' extraoesophageal symptoms and gastro-oesophageal reflux disease? Conversely, does the absence of abnormal acid exposure in the oesophagus suggest lack of such an association? Should the test be performed on or off therapy and does it matter? In this study, the role of pH monitoring in laryngitis, asthma, chronic cough and non-cardiac chest pain is examined and answers to the above questions are addressed based on current data.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:status
MEDLINE
pubmed:month
Mar
pubmed:issn
0269-2813
pubmed:author
pubmed:issnType
Print
pubmed:volume
23 Suppl 1
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
40-9
pubmed:meshHeading
pubmed:year
2006
pubmed:articleTitle
Review article: the role of pH monitoring in extraoesophageal gastro-oesophageal reflux disease.
pubmed:affiliation
Division of Gastroenterology and Hepatology, Center for Swallowing and Esophageal Disorders, Vanderbilt University Medical Center, Nashville, TN, USA. michael.vaezi@vanderbilt.edu
pubmed:publicationType
Journal Article, Review