| pubmed-article:16478679 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:16478679 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:16478679 | lifeskim:mentions | umls-concept:C0021853 | lld:lifeskim |
| pubmed-article:16478679 | lifeskim:mentions | umls-concept:C0441889 | lld:lifeskim |
| pubmed-article:16478679 | lifeskim:mentions | umls-concept:C0851285 | lld:lifeskim |
| pubmed-article:16478679 | lifeskim:mentions | umls-concept:C1709634 | lld:lifeskim |
| pubmed-article:16478679 | lifeskim:mentions | umls-concept:C0211726 | lld:lifeskim |
| pubmed-article:16478679 | lifeskim:mentions | umls-concept:C1454896 | lld:lifeskim |
| pubmed-article:16478679 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:16478679 | pubmed:dateCreated | 2006-4-17 | lld:pubmed |
| pubmed-article:16478679 | pubmed:abstractText | The anorectic lipid oleoylethanolamide and the orexigenic lipid anandamide both belong to the group of N-acylethanolamines that are generated by the enzyme N-acylphosphatidylethanolamine-hydrolyzing phospholipase D. The levels of the two bioactive lipids were investigated in rat intestines after 24 h of starvation as well as after 1 and 4 h of re-feeding. Total levels of precursor phospholipids and N-acylethanolamines were decreased upon food-deprivation whereas the level of the anandamide precursor molecule was significantly increased. The level of 2-arachidonoyl-glycerol was unchanged as was the activity of N-acyltransferase, N-acylphosphatidylethanolamine-hydrolyzing phospholipase D, and fatty acid amide hydrolase upon starvation and re-feeding. It is concluded that remodeling of the amide-linked fatty acids of N-acylphosphatidylethanolamine is responsible for the opposite effects on levels of anandamide and oleoylethanolamide in intestines of food-deprived rats and not an alternative biochemical route for anandamide synthesis. Furthermore, linoleoylethanolamide, which accounted for more than 50 mol% of the endogenous pool of N-acylethanolamines, was found not to have the same inhibitory effect on food intake, as did oleoylethanolamide following oral administration. | lld:pubmed |
| pubmed-article:16478679 | pubmed:language | eng | lld:pubmed |
| pubmed-article:16478679 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16478679 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:16478679 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16478679 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16478679 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16478679 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16478679 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16478679 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:16478679 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:16478679 | pubmed:month | Feb | lld:pubmed |
| pubmed-article:16478679 | pubmed:issn | 0006-3002 | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:HansenSteen... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:PetersenGitte... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:HansenHarald... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:Tang-Christen... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:SchmidPatrici... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:SchmidHarald... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:LarsenPhilip... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:SørensenCamil... | lld:pubmed |
| pubmed-article:16478679 | pubmed:author | pubmed-author:ArtmannAndrea... | lld:pubmed |
| pubmed-article:16478679 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:16478679 | pubmed:volume | 1761 | lld:pubmed |
| pubmed-article:16478679 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:16478679 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:16478679 | pubmed:pagination | 143-50; discussion 141-2 | lld:pubmed |
| pubmed-article:16478679 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:meshHeading | pubmed-meshheading:16478679... | lld:pubmed |
| pubmed-article:16478679 | pubmed:year | 2006 | lld:pubmed |
| pubmed-article:16478679 | pubmed:articleTitle | Intestinal levels of anandamide and oleoylethanolamide in food-deprived rats are regulated through their precursors. | lld:pubmed |
| pubmed-article:16478679 | pubmed:affiliation | Department of Pharmacology and Pharmacotherapy, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, 2100 Copenhagen, Denmark. | lld:pubmed |
| pubmed-article:16478679 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:16478679 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16478679 | lld:pubmed |
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| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:16478679 | lld:pubmed |
