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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
2
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pubmed:dateCreated |
2006-2-14
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pubmed:abstractText |
To determine whether adipose and red blood cell membrane lipids, particularly long-chain polyunsaturated fatty acids such as docosahexaenoic acid and eicosapentaenoic acid, are significantly correlated with phenotype in a family with autosomal dominant Stargardt macular dystrophy (gene locus STGD3). A mutation in the ELOVL4 gene is responsible for the macular dystrophy in this family, and its disease-causing mechanism may be its possible involvement in fatty acid elongation in the retina.
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0003-9950
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pubmed:author |
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pubmed:issnType |
Print
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pubmed:volume |
124
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
257-63
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pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:16476896-Adipose Tissue,
pubmed-meshheading:16476896-Adult,
pubmed-meshheading:16476896-Aged,
pubmed-meshheading:16476896-Diet Surveys,
pubmed-meshheading:16476896-Dietary Fats, Unsaturated,
pubmed-meshheading:16476896-Docosahexaenoic Acids,
pubmed-meshheading:16476896-Eicosapentaenoic Acid,
pubmed-meshheading:16476896-Erythrocyte Membrane,
pubmed-meshheading:16476896-Eye Proteins,
pubmed-meshheading:16476896-Female,
pubmed-meshheading:16476896-Gas Chromatography-Mass Spectrometry,
pubmed-meshheading:16476896-Genes, Dominant,
pubmed-meshheading:16476896-Humans,
pubmed-meshheading:16476896-Macular Degeneration,
pubmed-meshheading:16476896-Male,
pubmed-meshheading:16476896-Membrane Proteins,
pubmed-meshheading:16476896-Middle Aged,
pubmed-meshheading:16476896-Mutation,
pubmed-meshheading:16476896-Pedigree,
pubmed-meshheading:16476896-Phenotype,
pubmed-meshheading:16476896-Severity of Illness Index
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pubmed:year |
2006
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pubmed:articleTitle |
Association of adipose and red blood cell lipids with severity of dominant Stargardt macular dystrophy (STGD3) secondary to an ELOVL4 mutation.
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pubmed:affiliation |
Department of Foods and Nutrition, University of Utah, Salt Lake City, USA.
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pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
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