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rdf:type |
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lifeskim:mentions |
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pubmed:issue |
3
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pubmed:dateCreated |
2006-2-14
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pubmed:abstractText |
Hemochromatosis in white subjects is mostly due to homozygosity for the common C282Y substitution in HFE. Although clinical symptoms are preventable by early detection of the genetic predisposition and prophylactic treatment, population screening is not currently advocated because of the discrepancy between the common mutation prevalence and apparently lower frequency of clinical disease. This study compared screening for hemochromatosis in subjects with or without a family history.
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pubmed:grant |
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pubmed:commentsCorrections |
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pubmed:language |
eng
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pubmed:journal |
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pubmed:citationSubset |
AIM
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pubmed:chemical |
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pubmed:status |
MEDLINE
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pubmed:month |
Feb
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pubmed:issn |
0003-9926
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pubmed:author |
pubmed-author:AllenKatrina JKJ,
pubmed-author:AndersonGregory JGJ,
pubmed-author:BassettMark LML,
pubmed-author:CavanaughJuleen AJA,
pubmed-author:CrawfordDarrell HDH,
pubmed-author:DixonJeannette LJL,
pubmed-author:FletcherLinda MLM,
pubmed-author:HewettDavid GDG,
pubmed-author:LincolnDouglas JDJ,
pubmed-author:PowellLawrie WLW,
pubmed-author:PurdieDavid MDM,
pubmed-author:RammGrant AGA,
pubmed-author:SearleJeffrey WJW,
pubmed-author:Smolders-de HaasHH,
pubmed-author:SubramaniamV NathanVN
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pubmed:issnType |
Print
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pubmed:day |
13
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pubmed:volume |
166
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pubmed:owner |
NLM
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pubmed:authorsComplete |
Y
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pubmed:pagination |
294-301
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pubmed:dateRevised |
2007-11-14
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pubmed:meshHeading |
pubmed-meshheading:16476869-Adolescent,
pubmed-meshheading:16476869-Adult,
pubmed-meshheading:16476869-Age Factors,
pubmed-meshheading:16476869-Aged,
pubmed-meshheading:16476869-Alanine Transaminase,
pubmed-meshheading:16476869-Australia,
pubmed-meshheading:16476869-Biopsy,
pubmed-meshheading:16476869-Child,
pubmed-meshheading:16476869-Cohort Studies,
pubmed-meshheading:16476869-Female,
pubmed-meshheading:16476869-Ferritins,
pubmed-meshheading:16476869-Hemochromatosis,
pubmed-meshheading:16476869-Homozygote,
pubmed-meshheading:16476869-Humans,
pubmed-meshheading:16476869-Iron Overload,
pubmed-meshheading:16476869-Liver,
pubmed-meshheading:16476869-Liver Cirrhosis,
pubmed-meshheading:16476869-Longitudinal Studies,
pubmed-meshheading:16476869-Male,
pubmed-meshheading:16476869-Mass Screening,
pubmed-meshheading:16476869-Middle Aged,
pubmed-meshheading:16476869-ROC Curve,
pubmed-meshheading:16476869-Sensitivity and Specificity,
pubmed-meshheading:16476869-Sex Factors
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pubmed:year |
2006
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pubmed:articleTitle |
Screening for hemochromatosis in asymptomatic subjects with or without a family history.
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pubmed:affiliation |
Centre for the Advancement of Clinical Research, Royal Brisbane & Women's Hospital, Brisbane, Queensland 4029, Australia. Lawrie.Powell@qimr.edu.au
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pubmed:publicationType |
Journal Article,
Comparative Study,
Research Support, Non-U.S. Gov't,
Research Support, N.I.H., Extramural
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