| pubmed-article:1647227 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1647227 | lifeskim:mentions | umls-concept:C1704440 | lld:lifeskim |
| pubmed-article:1647227 | lifeskim:mentions | umls-concept:C0005821 | lld:lifeskim |
| pubmed-article:1647227 | lifeskim:mentions | umls-concept:C0270612 | lld:lifeskim |
| pubmed-article:1647227 | lifeskim:mentions | umls-concept:C0011570 | lld:lifeskim |
| pubmed-article:1647227 | lifeskim:mentions | umls-concept:C0020934 | lld:lifeskim |
| pubmed-article:1647227 | lifeskim:mentions | umls-concept:C1167622 | lld:lifeskim |
| pubmed-article:1647227 | pubmed:issue | 7 | lld:pubmed |
| pubmed-article:1647227 | pubmed:dateCreated | 1991-7-29 | lld:pubmed |
| pubmed-article:1647227 | pubmed:abstractText | We examined the relationship between platelet [3H]-imipramine binding and leukoencephalopathy as assessed by 1.5 Tesla Magnetic Resonance Imaging (MRI) in 21 elderly depressed patients who satisfied DSM-III criteria for major depression. Both drug-free platelet [3H]-imipramine binding and brain MRI studies were obtained during the same episode of depression. Our findings show a significant inverse relationship between frequency of subcortical hyperintensity (SCH) and the number (Bmax) of platelet [3H]-imipramine binding sites. Patients with Bmax less than 850 fmol/mg protein had significantly larger SCH compared with patients with a higher Bmax. These data provide further support to the potential use of platelet [3H]-imipramine binding studies and brain MR imaging as diagnostic adjuncts in geriatric depression and suggest, moreover, that these two biological markers may be linked in geriatric patients with depression. | lld:pubmed |
| pubmed-article:1647227 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1647227 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1647227 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1647227 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1647227 | pubmed:month | Apr | lld:pubmed |
| pubmed-article:1647227 | pubmed:issn | 0006-3223 | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:NemeroffC BCB | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:HusainM MMM | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:KrishnanK RKR | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:KnightD LDL | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:BoykoO BOB | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:McDonaldW MWM | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:FigielG SGS | lld:pubmed |
| pubmed-article:1647227 | pubmed:author | pubmed-author:DoraiswamyP... | lld:pubmed |
| pubmed-article:1647227 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1647227 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:1647227 | pubmed:volume | 29 | lld:pubmed |
| pubmed-article:1647227 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1647227 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1647227 | pubmed:pagination | 665-70 | lld:pubmed |
| pubmed-article:1647227 | pubmed:dateRevised | 2007-11-14 | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:meshHeading | pubmed-meshheading:1647227-... | lld:pubmed |
| pubmed-article:1647227 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1647227 | pubmed:articleTitle | Platelet [3H]-imipramine binding and leukoencephalopathy in geriatric depression. | lld:pubmed |
| pubmed-article:1647227 | pubmed:affiliation | Department of Psychiatry, Duke University Medical Center, Durham, NC 27710. | lld:pubmed |
| pubmed-article:1647227 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1647227 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:1647227 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
