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Predicate | Object |
---|---|
rdf:type | |
lifeskim:mentions | |
pubmed:issue |
7
|
pubmed:dateCreated |
1991-7-22
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pubmed:abstractText |
Four cases of advanced hepatocellular carcinoma patients were treated by intra-portal infusion of 5-FU immediately after surgery. 5-FU at 120-250 mg daily was injected continuously via portal catheter from postoperative day 4 to 21. Two cases with short administration period of 4 days died of recurrence on the residual liver at 9 and 7 months after hepatic resection. Another 2 cases with a total amount of 5-FU at 2,165 mg and 2,250 mg, respectively, survived 4 years 3 months and 4 year 8 months each. Mild leukocytopenia and transient liver dysfunction were found as side effects. Intraportal infusion of anticancer drugs is a promising means to prevent intrahepatic micrometastasis after resection of hepatocellular carcinoma.
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pubmed:language |
jpn
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pubmed:journal | |
pubmed:citationSubset |
IM
|
pubmed:chemical | |
pubmed:status |
MEDLINE
|
pubmed:month |
Jun
|
pubmed:issn |
0385-0684
|
pubmed:author | |
pubmed:issnType |
Print
|
pubmed:volume |
18
|
pubmed:owner |
NLM
|
pubmed:authorsComplete |
Y
|
pubmed:pagination |
1195-8
|
pubmed:dateRevised |
2006-11-15
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pubmed:meshHeading |
pubmed-meshheading:1647151-Adult,
pubmed-meshheading:1647151-Carcinoma, Hepatocellular,
pubmed-meshheading:1647151-Combined Modality Therapy,
pubmed-meshheading:1647151-Female,
pubmed-meshheading:1647151-Fluorouracil,
pubmed-meshheading:1647151-Follow-Up Studies,
pubmed-meshheading:1647151-Hepatectomy,
pubmed-meshheading:1647151-Humans,
pubmed-meshheading:1647151-Infusions, Intravenous,
pubmed-meshheading:1647151-Liver Neoplasms,
pubmed-meshheading:1647151-Male,
pubmed-meshheading:1647151-Middle Aged,
pubmed-meshheading:1647151-Portal Vein
|
pubmed:year |
1991
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pubmed:articleTitle |
[Intraportal vein infusion chemotherapy after hepatectomy for hepatocellular carcinoma--preliminary report].
|
pubmed:affiliation |
1st Dept. of Surgery, Hokkaido University School of Medicine.
|
pubmed:publicationType |
Journal Article,
English Abstract
|