Statements in which the resource exists as a subject.
PredicateObject
rdf:type
lifeskim:mentions
pubmed:issue
1
pubmed:dateCreated
2006-2-9
pubmed:abstractText
MS-222 (tricaine methane sulfonate) is an agent commonly used to anaesthetise or euthanize amphibians used in experiments. It is administered by immersing the animal to allow absorption through the skin. Chytridiomycosis is an important disease of amphibians and research involves experiments with live animals. Batrachochytrium dendrobatidis, the fungus which causes chytridiomycosis, is located in the skin and therefore the organism should come into contact with MS-222 when it is used. B. dendrobatidis is a sensitive organism which could possibly be killed by MS-222. Hence, results of chytridiomycosis studies in which MS-222 is used could be unreliable. A concentration of 2 g l(-1) and an exposure duration of 1 h is at the high end of the range at which MS-222 would be most commonly used. Exposure to 2 g l(-1) MS-222 for 1 h does not kill B. dendrobatidis cultures, suggesting that MS-222 is safe to use in chytridiomycosis studies.
pubmed:language
eng
pubmed:journal
pubmed:citationSubset
IM
pubmed:chemical
pubmed:status
MEDLINE
pubmed:month
Dec
pubmed:issn
0177-5103
pubmed:author
pubmed:issnType
Print
pubmed:day
30
pubmed:volume
68
pubmed:owner
NLM
pubmed:authorsComplete
Y
pubmed:pagination
89-90
pubmed:dateRevised
2006-11-15
pubmed:meshHeading
pubmed:year
2005
pubmed:articleTitle
MS-222 (tricaine methane sulfonate) does not kill the amphibian chytrid fungus Batrachochytrium dendrobatidis.
pubmed:affiliation
Amphibian Disease Ecology Group, School of Public Health, Tropical Medicine and Rehabilitation Sciences, James Cook University, Townsville, Queensland 4811, Australia. rebecca.webb1@jcu.edu.au
pubmed:publicationType
Journal Article, Research Support, Non-U.S. Gov't